CAS 88899-22-3

N-benzoyl-phe-val-arg 7-amido-4-*methylcoumarin

Description:

N-benzoyl-phe-val-arg 7-amido-4-methylcoumarin, identified by its CAS number 88899-22-3, is a synthetic compound that belongs to the class of peptide derivatives. This substance features a coumarin moiety, which is known for its fluorescent properties, making it useful in various biochemical applications, particularly in the study of enzyme activity and protein interactions. The presence of the benzoyl group and the amino acid sequence (phenylalanine, valine, and arginine) suggests that it may serve as a substrate or inhibitor for specific proteolytic enzymes. The compound's structure allows for potential interactions with biological macromolecules, contributing to its utility in research settings. Additionally, the 7-amido position on the coumarin ring enhances its solubility and reactivity, which can be advantageous in experimental protocols. Overall, N-benzoyl-phe-val-arg 7-amido-4-methylcoumarin is characterized by its unique structural features that facilitate its role in biochemical assays and studies involving peptide interactions.

Formula: C₃₇H₄₃N₇O₆

Synonyms:

• Bz-Phe-Val-Arg-AMC

Bz-Phe-Val-Arg-AMC

CAS: 88899-22-3

Sensitive fluorogenic substrate for the quantitative determination of thrombin. Bz-FVR-AMC is also cleaved by ficain.

Formula: C₃₇H₄₃N₇O₆

Purity: 98.6%

Color and Shape: White Powder

Molecular weight: 681.79

Ref: 01-4003131

Bz-FVR-AMC

CAS: 88899-22-3

Bz-FVR-AMC

Purity: 97%

Molecular weight: 681.79g/mol

Ref: 54-OR1074246

Bz-FVR-AMC

CAS: 88899-22-3

Bz-FVR-AMC: a fluorogenic procathepsin substrate, kcat/Km = 1070 mM^-1s^-1; high levels inhibit. Store in dark.

Formula: C₃₇H₄₃N₇O₆

Color and Shape: Solid

Molecular weight: 681.78

Ref: TM-T75373

Bz-Phe-Val-Arg-AMC hydrochloride salt

CAS: 88899-22-3

Bz-Phe-Val-Arg-AMC is a synthetic substrate that is used to measure proteolytic activity. It has been shown to be hydrolyzed by serine proteases, such as trypsin and chymotrypsin, at a rate proportional to the enzyme's concentration. The rate of hydrolysis was determined using a kinetic assay in which the release of AMC from the peptide bond was measured using an ultraviolet spectrophotometer. Bz-Phe-Val-Arg-AMC has also been used to study the effects of various food additives on proteolytic activity. This test can be used as a diagnostic tool for inflammatory diseases, such as Crohn's disease and ulcerative colitis.

Formula: C₃₇H₄₃N₇O₆

Purity: Min. 95%

Molecular weight: 681.78 g/mol

Ref: 3D-FB110481