CAS 88903-69-9

(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine

Description:

The chemical substance with the name "(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine" and CAS number "88903-69-9" is a complex organic compound characterized by its intricate polycyclic structure, which includes multiple fused rings and functional groups. This compound features a dioxacyclo structure, indicating the presence of ether linkages within its cyclic framework. The stereochemistry is specified by the multiple chiral centers, which contribute to its three-dimensional conformation and potentially influence its biological activity. Such compounds often exhibit unique properties, including specific solubility profiles, reactivity, and potential pharmacological effects. The presence of ethano groups suggests that it may participate in various chemical reactions, making it of interest in synthetic organic chemistry and medicinal chemistry. Overall, the complexity of its structure may lead to diverse applications, particularly in the development of novel therapeutic agents or materials.

Formula: C₂₈H₅₀N₂O₂

InChI: InChI=1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24+,25-,26-,27+,28+/m1/s1

InChI key: InChIKey=PQYOPBRFUUEHRC-HCKQMYSWSA-N

SMILES: [C@@]12([N@@]3CC[C@](O1)(CCCCCC[C@]4([C@@]5(O[C@](CCCCCC[C@]2(CCC3)[H])(CC[N@]5CCC4)[H])[H])[H])[H])[H]

Synonyms:

• (-)-Araguspongin E
• (-)-Araguspongine E
• (-)-Xestospongin C
• (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine
• (1R,8R,10S,15S,22R,29S)-9,30-Dioxa-11,25-diazapentacyclo[20.6.2.2~8,11~.0~10,15~.0~25,29~]dotriacontane
• 5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[10,9-b:20,19-b']dipyridine, eicosahydro-, (4aR,11R,12aS,16aS,23R,24aS)-
• 5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine, eicosahydro-, (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-
• 5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine, eicosahydro-, [1R-(1R*,4aR*,11R*,12aS*,13S*,16aS*,23R*,24aS*)]-
• Xestospongine C

Xestospongin C

CAS: 88903-69-9

Formula: C₂₈H₅₀N₂O₂

Molecular weight: 446.7088

Ref: IN-DA00491B

Xestospongin C

CAS: 88903-69-9

Formula: C₂₈H₅₀N₂O₂

Molecular weight: 446.71

Ref: 7W-GL4625

Xestospongin C

Controlled Product

CAS: 88903-69-9

Formula: C₂₈H₅₀N₂O₂

Color and Shape: Neat

Molecular weight: 179.216

Ref: TR-X744455

(-)-Xestospongin C

CAS: 88903-69-9

(-)-Xestospongin C is a surface-active molecule that has been shown to be membrane permeable. When applied to the surface of cells, it acts as a mimic for natural sphingolipids. (-)-Xestospongin C binds to the ryanodine receptor and blocks its activation by calcium ions, leading to inhibition of Ca2+ release from intracellular stores. It also inhibits the response of glycosidic bond-containing proteins in glycoprotein synthesis by inhibiting protein phosphorylation and subsequent dephosphorylation. (-)-Xestospongin C has been shown to have anti-inflammatory properties in models of inflammatory diseases such as ischemia reperfusion injury, which may be due to its ability to inhibit the production of proinflammatory cytokines such as IL-1β and TNFα.

Formula: C₂₈H₅₀N₂O₂

Purity: 90%Min

Molecular weight: 446.71 g/mol

Ref: 3D-NDA90369

Xestospongin C

CAS: 88903-69-9

Xestospongin C ((-)-Xestospongin C) is an IP3R inhibitor and also a SERCA (sarco/endoplasmic reticulum Ca2+ ATPase) inhibitor.

Formula: C₂₈H₅₀N₂O₂

Purity: 98%

Color and Shape: Off-White

Molecular weight: 446.71

Ref: TM-T23538