CAS 88919-22-6

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide

Description:

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide, with the CAS number 88919-22-6, is a chemical compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This compound features a sulfonamide functional group, which is known for its biological activity, particularly in medicinal chemistry. The presence of the aminoethyl side chain and the N-methyl group contributes to its potential interactions with biological targets, making it of interest in pharmaceutical research. The sulfonamide moiety can enhance solubility and bioavailability, while the indole core is often associated with various pharmacological properties, including anti-inflammatory and antimicrobial activities. The compound's molecular structure suggests it may participate in hydrogen bonding and other intermolecular interactions, influencing its reactivity and stability. Overall, this compound's unique structural features position it as a candidate for further investigation in drug development and therapeutic applications.

Formula: C₁₂H₁₇N₃O₂S

InChI: InChI=1S/C12H17N3O2S/c1-14-18(16,17)8-9-2-3-12-11(6-9)10(4-5-13)7-15-12/h2-3,6-7,14-15H,4-5,8,13H2,1H3

InChI key: InChIKey=MURZXKIEJFJMPP-UHFFFAOYSA-N

SMILES: C(CN)C=1C=2C(NC1)=CC=C(CS(NC)(=O)=O)C2

Synonyms:

• 1-[3-(2-Aminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide
• 1H-Indole-5-methanesulfonamide, 3-(2-aminoethyl)-N-methyl-
• 3-(2-Aminoethyl)-N-Methyl-1H-Indole-5-Methanesulfonamide

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide

CAS: 88919-22-6

Formula: C₁₂H₁₇N₃O₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 267.3473

Ref: IN-DA00488O

Sumatriptan EP Impurity E

CAS: 88919-22-6

Formula: C₁₂H₁₇N₃O₂S

Color and Shape: Pale Yellow Solid

Molecular weight: 267.35

Ref: 4Z-S-1110

Sumatriptan Succinate EP Impurity E

Controlled Product

CAS: 88919-22-6

Formula: C₁₂H₁₇N₃O₂S

Color and Shape: Neat

Molecular weight: 267.35

Ref: 86-MM0310.05

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (Didesmethyl Sumatriptan)

Controlled Product

CAS: 88919-22-6

Impurity Sumatriptan EP Impurity E
Applications 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (Didesmethyl Sumatriptan) (Sumatriptan EP Impurity E) is an antimigraine agent. A Sumatriptan intermediate.

Formula: C₁₂H₁₇N₃O₂S

Color and Shape: Light Yellow To Brown

Molecular weight: 267.35

Ref: TR-A609165

1-(3-(2-Aminoethyl)-1H-indol-5-yl)-N-methylmethanesulfonamide

CAS: 88919-22-6

Formula: C₁₂H₁₇N₃O₂S

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 267.35

Ref: 10-F078734

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide

CAS: 88919-22-6

3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (AMIS) is an intermediate in the preparation of medicaments. It is a stable process and can be used as an intermediate for other compounds. AMIS is prepared by reacting methanesulfonic acid with methanol and ammonium carbonate, which produces methanesulfonamide, succinic acid and ammonium hydroxide. The reaction liquid is then heated to produce a crystalline solid. The crystals are then recrystallized to yield AMIS as a white solid.

Formula: C₁₂H₁₇N₃O₂S

Purity: Min. 95%

Color and Shape: Off-White To Beige To Light Brown Solid

Molecular weight: 267.35 g/mol

Ref: 3D-FA33265

Sumatriptan EP Impurity E

CAS: 88919-22-6

Formula: C₁₂H₁₇N₃O₂S

Molecular weight: 267.35

Ref: ST-EA-CP-S13005