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CAS 89-57-6

:

5-Aminosalicylic acid

Description:
5-Aminosalicylic acid (5-ASA), with the CAS number 89-57-6, is an organic compound that belongs to the class of salicylates. It is characterized by the presence of both an amino group (-NH2) and a carboxylic acid group (-COOH) attached to a benzene ring, specifically at the 5 and 2 positions, respectively. This compound is a white to off-white crystalline powder that is soluble in water and exhibits weak acidity. 5-ASA is primarily known for its role as a therapeutic agent in the treatment of inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, due to its anti-inflammatory properties. It functions by inhibiting the production of inflammatory mediators and promoting mucosal healing. Additionally, 5-ASA can undergo various chemical reactions, including acetylation and esterification, which can modify its pharmacological properties. Its safety profile is generally favorable, although side effects may occur in some patients. Overall, 5-aminosalicylic acid is a significant compound in both medicinal chemistry and therapeutic applications.
Formula:C7H7NO3
InChI:InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
InChI key:InChIKey=KBOPZPXVLCULAV-UHFFFAOYSA-N
SMILES:C(O)(=O)C1=C(O)C=CC(N)=C1
Synonyms:
  • 2-Hydroxy-5-aminobenzoic acid
  • 3-Carboxy-4-hydroxyaniline
  • 5-Amino Saliclic Acid
  • 5-Amino salicylic Acid
  • 5-Amino salicylic acidl
  • 5-Amino-2-Hydroxybenzoate
  • 5-Amino-2-hydroxybenzoic acid
  • 5-Aminosalicylsaeure
  • 5-Aminosalicylsaure
  • 5-Asa
  • See more synonyms
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  • Mesalazine
    Biosynth
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    Mesalazine

    CAS:
    Mesalazine is an anti-inflammatory drug, which is a derivative of 5-aminosalicylic acid (5-ASA). It is sourced synthetically through aminosalicylic compound modification. The mode of action of mesalazine involves its ability to act topically on the colonic epithelium to inhibit leukotriene synthesis and block cyclooxygenase pathways. This suppresses the production of pro-inflammatory cytokines and reactive oxygen species in the gut mucosa.Mesalazine is primarily used in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It helps in reducing inflammation, thus controlling symptoms like diarrhea, rectal bleeding, and abdominal pain. The ability of mesalazine to target specific sites within the intestines and its efficacy in maintaining remission makes it a vital therapeutic agent in gastroenterology.
    Formula:C7H7NO3
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:153.14 g/mol

    Ref: 3D-FM25111

    100g
    169.00€
    2kg
    557.00€
    5kg
    962.00€
    10kg
    1,502.00€