CAS 89-77-0

2-Amino-4-chlorobenzoic acid

Description:

2-Amino-4-chlorobenzoic acid, also known as 4-chloroanthranilic acid, is an aromatic amino acid derivative characterized by the presence of both an amino group (-NH2) and a carboxylic acid group (-COOH) attached to a benzene ring that also contains a chlorine substituent. Its molecular formula is C7H6ClN1O2, and it features a chlorinated benzene structure, which contributes to its unique chemical properties. This compound is typically a white to off-white crystalline solid that is soluble in water and organic solvents, depending on pH. It exhibits acidic behavior due to the carboxylic acid group and can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. 2-Amino-4-chlorobenzoic acid is used in the synthesis of dyes, pharmaceuticals, and agrochemicals, and it serves as an important intermediate in organic synthesis. Additionally, it may exhibit biological activity, making it of interest in medicinal chemistry and research applications.

Formula: C₇H₆ClNO₂

InChI: InChI=1S/C7H6ClNO2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,9H2,(H,10,11)

InChI key: InChIKey=JYYLQSCZISREGY-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(N)C=C(Cl)C=C1

Synonyms:

• 2,4-Acba
• 2-Amino-4-Chloro-Benzoicacid
• 2-Amino-4-Chlorobenzoate
• 2-Amino-4-Chlorobenzoicacid
• 2-Carboxy-5-Chloroaniline
• 3-Amino-4-Carboxy-1-Chlorobenzene
• 4-Chloro-2-Aminobenzoic
• 4-Chloro-2-Aminobenzoic Acid
• 4-Chloro-Anthranilicaci
• 4-Chloroanthranil Acid
• 4-Chloroanthranilic Acid
• 4-Chloroanthranilicacid
• Anthranilic Acid, 4-Chloro-
• Benzoic Acid, 2-Amino-4-Chloro-
• NSC 17188
• P-Chloro-O-Amino Benzoic Acid
• Rarechem Al Bo 0400

2-Amino-4-chlorobenzoic Acid

CAS: 89-77-0

Formula: C₇H₆ClNO₂

Purity: min. 98.0 area%(HPLC)

Color and Shape: White to Light yellow to Dark green powder to crystal

Molecular weight: 171.58

Ref: 3B-A0661

2-Amino-4-chlorobenzoic acid, 98%

CAS: 89-77-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₆ClNO₂

Purity: 98%

Color and Shape: Pale cream to cream to pale brown, Powder

Molecular weight: 171.58

Ref: 02-A10201

2-Amino-4-Chlorobenzoic Acid

CAS: 89-77-0

Formula: C₇H₆ClNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 171.5810

Ref: IN-DA003339

2-Amino-4-chlorobenzoic acid

CAS: 89-77-0

Formula: C₇H₆ClNO₂

Molecular weight: 171.58

Ref: 7W-GM3106

2-Amino-4-chlorobenzoic acid

CAS: 89-77-0

2-Amino-4-chlorobenzoic acid

Formula: C₇H₆ClNO₂

Purity: 98%

Color and Shape: off-white solid

Molecular weight: 171.58g/mol

Ref: 54-OR21298

2-Amino-4-chlorobenzoic Acid

Controlled Product

CAS: 89-77-0

Applications 2-Amino-4-chlorobenzoic Acid is used in the preparation of quinazolinone derivatives observed to be useful in the treatment of Alzheimer’s disease. Also it aids in the synthesis of non-nucleoside, thumb pocket 2 HCV NS5B polymerase inhibitors used in Hepatitis C therapy.
References Stammers, T. et al.: Bioorg, Med, Chem. Lett., 23, 2585 (2013);

Formula: C₇H₆ClNO₂

Color and Shape: Neat

Molecular weight: 171.58

Ref: TR-A603295

4-Chloroanthranilic acid

CAS: 89-77-0

4-Chloroanthranilic acid is an inorganic acid that has antimicrobial properties. It is a bound form of anthranilic acid, which is not water soluble and can be easily absorbed by the skin. 4-Chloroanthranilic acid is used as an antibiotic in topical preparations because it has been shown to have inhibitory effects on the growth of P. aeruginosa, epidermal growth factor, and nitrogen atoms. 4-Chloroanthranilic acid also has coordination complex with copper and inhibits the growth of bacteria by inhibiting the production of bacterial cell wall synthesis enzymes.

Formula: C₇H₆ClNO₂

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 171.58 g/mol

Ref: 3D-FC45151

2-Amino-4-chlorobenzoic acid

CAS: 89-77-0

2-Amino-4-chlorobenzoic acid is a versatile and useful building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.

Formula: C₇H₆ClNO₂

Purity: Min. 98 Area-%

Molecular weight: 171.58 g/mol

Ref: 3D-A-5331

2-Amino-4-chlorobenzoic acid

CAS: 89-77-0

Formula: C₇H₆ClNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 171.58

Ref: 10-F011358