CAS 890707-28-5

2-Amino-5-chloro-N,3-dimethylbenzamide

Description:

2-Amino-5-chloro-N,3-dimethylbenzamide is an organic compound characterized by its amide functional group, which is derived from benzoic acid. This compound features a benzene ring substituted with an amino group at the 2-position, a chlorine atom at the 5-position, and two methyl groups at the 3-position. The presence of the amino group contributes to its basicity, while the chlorine atom introduces electronegative characteristics that can influence its reactivity and solubility. The dimethyl substitution enhances its steric properties, potentially affecting its interactions with biological targets. This compound may exhibit various biological activities, making it of interest in pharmaceutical research. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of new therapeutic agents. Additionally, the compound's stability and solubility in organic solvents can vary, which is important for its practical applications in synthesis and formulation. As with many organic compounds, safety and handling precautions should be observed due to potential toxicity or reactivity.

Formula: C₉H₁₁ClN₂O

InChI: InChI=1S/C9H11ClN2O/c1-5-3-6(10)4-7(8(5)11)9(13)12-2/h3-4H,11H2,1-2H3,(H,12,13)

InChI key: InChIKey=WOBVZGBINMTNKL-UHFFFAOYSA-N

SMILES: C(NC)(=O)C1=C(N)C(C)=CC(Cl)=C1

Synonyms:

• 2-Amino-5-chloro-N,3-dimethylhenzamide
• 2-Amino-5-chloro-N-methyl-3-methylbenzamide
• Benzamide, 2-amino-5-chloro-N,3-dimethyl-
• 2-Amino-5-chloro-N,3-dimethylbenzamide
• Bardoxolone Powder C9h11cln2o
• 2-Amino-5-chloro-N,3-dimethylbenzamide 98%

2-Amino-5-chloro-N,3-dimethylbenzamide

CAS: 890707-28-5

Formula: C₉H₁₁ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 198.6494

Ref: IN-DA0040OP

2-Amino-5-chloro-N,3-dimethylbenzamide

CAS: 890707-28-5

2-Amino-5-chloro-N,3-dimethylbenzamide

Purity: 95%

Molecular weight: 198.65g/mol

Ref: 54-OR52935

Chlorantraniliprole Impurity 5

CAS: 890707-28-5

Formula: C₉H₁₁ClN₂O

Molecular weight: 198.65

Ref: 4Z-C-464009

2-Amino-5-chloro-N,3-dimethylbenzamide

Controlled Product

CAS: 890707-28-5

Applications 2-Amino-5-chloro-N,3-dimethylbenzamide is the key intermediate used in the synthesis of chlorantraniliprole, a novel insecticide.
References Zhang, T., et al.: Jingxi Huagong Zhongjianti, 40, 17 (2010); Peng, Y., et al.: Nongyao, 48, 326 (2009)

Formula: C₉H₁₁ClN₂O

Color and Shape: Neat

Molecular weight: 198.649

Ref: TR-A100190

2-Amino-5-chloro-N,3-dimethylbenzamide

CAS: 890707-28-5

Formula: C₉H₁₁ClN₂O

Purity: 98%

Molecular weight: 198.65

Ref: 10-F210358

Chlorantraniliprole Impurity 2

CAS: 890707-28-5

Formula: C₉H₁₁ClN₂O

Molecular weight: 198.65

Ref: ST-EA-CP-C223002

2-Amino-5-chloro-N,3-dimethylbenzamide

CAS: 890707-28-5

2-Amino-5-chloro-N,3-dimethylbenzamide is a synthetic compound. It has been shown to induce necrotic cell death in mammalian cells. This compound was synthesized by the reaction of 2-aminoquinoline with a Grignard reagent, followed by nitration of the resultant amine. The synthesis of this compound was thermodynamically favorable and exhibited good solubility in water. The chlorantraniliprole and anthranilic acid moieties are activated with an acylation reaction, which allows them to bind to the ryanodine receptor and inhibit calcium release from the sarcoplasmic reticulum (SR) with ammonolysis. This inhibition leads to ferroptosis, a type of programmed necrosis.

Formula: C₉H₁₁ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 198.65 g/mol

Ref: 3D-FA159371