CAS 891494-63-6

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinylpyrazolo[1,5-a]pyrimidin-7-amine

Description:

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinylpyrazolo[1,5-a]pyrimidin-7-amine is a chemical compound characterized by its complex structure, which includes a pyrazolo-pyrimidine core. This compound features a bromine atom at the 6-position and a piperidine ring at the 5-position, contributing to its potential biological activity. The presence of the 1-methyl-1H-pyrazol-4-yl group suggests that it may interact with various biological targets, possibly influencing signaling pathways or enzyme activities. The compound's molecular structure indicates it may exhibit properties such as solubility in organic solvents, and it may be of interest in medicinal chemistry for its potential therapeutic applications. Its CAS number, 891494-63-6, allows for easy identification in chemical databases. Overall, this compound's unique structural features may contribute to its pharmacological properties, making it a candidate for further research in drug development.

Formula: C₁₅H₁₈BrN₇

Synonyms:

• Pyrazolo[1,5-a]pyrimidin-7-amine, 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinyl-

MK-8776 (SCH 900776)

CAS: 891494-63-6

Formula: C₁₅H₁₈BrN₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 376.2543

Ref: IN-DA00GU6F

6-Bromo-3-(1-Methyl-1H-Pyrazol-4-Yl)-5-(3R)-3-Piperidinylpyrazolo[1,5-a]Pyrimidin-7-Amine

CAS: 891494-63-6

6-Bromo-3-(1-Methyl-1H-Pyrazol-4-Yl)-5-(3R)-3-Piperidinylpyrazolo[1,5-a]Pyrimidin-7-Amine

Purity: 99%

Molecular weight: 376.25g/mol

Ref: 54-OR1024270

SCH900776

CAS: 891494-63-6

SCH900776

Purity: ≥95%

Molecular weight: 376.25g/mol

Ref: 54-BUP07968

SCH900776

CAS: 891494-63-6

Ref: 7W-GW5917

SCH900776

CAS: 891494-63-6

SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.

Formula: C₁₅H₁₈BrN₇

Purity: 96.69% - 99.6%

Color and Shape: Solid

Molecular weight: 376.25

Ref: TM-T2517

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinylpyrazolo[1,5-a]pyrimidin-7-amine

CAS: 891494-63-6

Formula: C₁₅H₁₈BrN₇

Purity: 99%

Molecular weight: 376.262

Ref: 10-F498848

6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinylpyrazolo[1,5-a]pyrimidin-7-amine-13C2,15N2

Controlled Product

CAS: 891494-63-6

Formula: C₂C₁₃H₁₈Br₁₅N₂N₅

Color and Shape: Neat

Molecular weight: 380.226

Ref: TR-B685537

MK-8776 (SCH 900776)

CAS: 891494-63-6

MK-8776 is a potent inhibitor of the enzyme, protein kinase C (PKC). It was developed as an anticancer agent and has shown significant cytotoxicity against various cancer cell lines. MK-8776 can inhibit the cell factor, which is involved in checkpoint control of cell proliferation and differentiation. This drug also inhibits the ability of cancer cells to maintain their mitochondrial membrane potential, which leads to apoptosis. MK-8776 has been shown to be effective against hepatocyte-like cells and squamous carcinoma.

Formula: C₁₅H₁₈BrN₇

Purity: Min. 95%

Molecular weight: 376.25 g/mol

Ref: 3D-RKB49463