CAS 89159-60-4

(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol

Description:

(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol, with the CAS number 89159-60-4, is an organic compound that belongs to the indole family, characterized by its complex structure featuring an indole ring substituted with a methyl group, a nitro group, and a phenyl group. This compound exhibits properties typical of indole derivatives, including potential biological activity, which may include antimicrobial or anticancer effects, although specific biological data would depend on empirical studies. The presence of the nitro group suggests potential reactivity, particularly in reduction reactions, while the hydroxymethyl group can participate in hydrogen bonding and may influence solubility and reactivity. The compound's molecular structure indicates it may be lipophilic due to the phenyl group, which could affect its pharmacokinetics if studied for medicinal applications. Overall, (1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol is of interest in both synthetic organic chemistry and medicinal chemistry for its potential applications and reactivity.

Formula: C₁₆H₁₄N₂O₃

InChI: InChI=1/C16H14N2O3/c1-17-14-8-7-12(18(20)21)9-13(14)16(15(17)10-19)11-5-3-2-4-6-11/h2-9,19H,10H2,1H3

SMILES: Cn1c2ccc(cc2c(c2ccccc2)c1CO)N(=O)=O

Synonyms:

• {5-nitro-1-methyl-3-phenyl-1H-indol-2-yl}methanol
• 1H-indole-2-methanol, 1-methyl-5-nitro-3-phenyl-

1H-Indole-2-methanol, 1-methyl-5-nitro-3-phenyl-

CAS: 89159-60-4

Formula: C₁₆H₁₄N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 282.2940

Ref: IN-DA003WOK

ML-354

CAS: 89159-60-4

ML-354

Purity: ≥98%

Molecular weight: 282.29g/mol

Ref: 54-BUP07260

ML-354

Controlled Product

CAS: 89159-60-4

Formula: C₁₆H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 418.435

Ref: TR-M425360

ML354

CAS: 89159-60-4

ML354 is a novel serine protease inhibitor that blocks the activity of the thrombin receptor by competitive inhibition. It has been shown to inhibit protease activity in rat cardiomyocytes and human cancer cells, as well as in vitro models of inflammatory bowel disease. ML354 also inhibits the activation of wild-type mice heart following ischemia reperfusion injury. ML354's mechanism of action is believed to be due to its ability to bind irreversibly with a specific site on the active site of thrombin, preventing binding with other substrates and thus inhibiting thrombin's enzymatic activity.

Formula: C₁₆H₁₄N₂O₃

Purity: Min. 95%

Molecular weight: 282.29 g/mol

Ref: 3D-PDA15960

ML-354

CAS: 89159-60-4

ML354 is a selective antagonist of PAR4 with an IC 50 of 140 nM [1].

Formula: C₁₆H₁₄N₂O₃

Purity: 99.44%

Color and Shape: Solid

Molecular weight: 282.29

Ref: TM-T21901