CAS 89186-34-5

1H-Imidazole, 1-[3-[(4-hydroxy-2-oxobutyl)amino]-1-oxo-2-propenyl]-

Description:

1H-Imidazole, 1-[3-[(4-hydroxy-2-oxobutyl)amino]-1-oxo-2-propenyl]- is a chemical compound characterized by its imidazole ring, which is a five-membered heterocyclic structure containing two nitrogen atoms. This compound features a side chain that includes a 4-hydroxy-2-oxobutyl group linked to an amino group, contributing to its potential biological activity. The presence of the 1-oxo-2-propenyl moiety suggests reactivity that may be relevant in various chemical reactions, particularly in the context of medicinal chemistry. The compound's structure indicates it may exhibit properties such as solubility in polar solvents, and it may participate in hydrogen bonding due to the hydroxyl group. Its CAS number, 89186-34-5, allows for easy identification in chemical databases. Overall, this compound may be of interest in pharmaceutical research, particularly for its potential applications in drug development or as a biochemical probe.

Formula: C₁₀H₁₃N₃O₃

1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole(mixture E/Z)

CAS: 89186-34-5

Formula: C₁₀H₁₃N₃O₃

Color and Shape: Solid

Molecular weight: 223.2285

Ref: IN-DA003W08

1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole(mixture E/Z)

Controlled Product

CAS: 89186-34-5

Stability Light Sensitive
Applications Clavulanic acid (C563750) impurity as a alkaline degradation product.
References Haginaka, J., et al.: Chem. Pharm. Bull., 31, 4436 (1983),

Formula: C₁₀H₁₃N₃O₃

Color and Shape: Neat

Molecular weight: 223.23

Ref: TR-A798900

1-(4-Aza-8-hydroxy-6-oxo)oct-2-en-1-oylimidazole

CAS: 89186-34-5

The 1-aza-8-hydroxy-6-oxo-oct-2-en-1-oylimidazole is a prodrug that is hydrolyzed to form the active compound clavulanate. It can be used for the treatment of infections caused by beta lactamase producing bacteria such as penicillinase producing staphylococci and beta lactamase producing streptococci. The 1-(4-Aza)8-(6-oxo)oct-(2)en-(1)-oylimidazole binds to penicillin binding proteins, which prevents the formation of an antibiotic inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. The clavulanic acid moiety in this drug also inhibits beta lactamases produced by bacteria, resulting in increased efficacy against these organisms.

Formula: C₁₀H₁₃N₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 223.23 g/mol

Ref: 3D-PDA18634