CAS 89196-78-1

pyruvic-2,3-13C2 acid, sodium salt

Description:

Pyruvic-2,3-^13C2 acid, sodium salt, is a stable isotopically labeled derivative of pyruvic acid, which is a key intermediate in various metabolic pathways, particularly in glycolysis. The presence of the ^13C isotopes at the 2 and 3 positions allows for enhanced tracking and analysis in metabolic studies using techniques such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. As a sodium salt, it is typically more soluble in aqueous solutions compared to its acid form, facilitating its use in biological and biochemical applications. This compound is characterized by its relatively low molecular weight and is generally considered non-toxic at standard laboratory concentrations. It plays a significant role in research related to metabolism, energy production, and the study of metabolic flux. Additionally, its isotopic labeling can provide insights into metabolic pathways and the dynamics of carbon flow in biological systems.

Formula: C₁₃C₂H₃NaO₃

InChI: InChI=1/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/i1+1,2+1;

SMILES: CC(=O)C(=O)O.[Na]

Synonyms:

• sodium 2-oxo(2,3-13C2)propanoate
• Pyruvic-2,3-13C2 acid sodium salt

2-Oxopropanoate-13c2 (sodium)

CAS: 89196-78-1

Formula: C₃H₃NaO₃

Color and Shape: Solid

Molecular weight: 112.0292

Ref: IN-DA003VZ8

6 Pyruvic Acid Sodium Salt-13C2

CAS: 89196-78-1

Applications Pyruvic Acid-13C2 is an intermediate in synthesizing L-Lactic Acid-d3 Sodium Salt (L113503), a labelled sodium salt of L-Lactic Acid (L113500). L-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and other organs and body fluids.
References Wenzel, A., et al.: J. Neurosci., 21, 53 (2001); Martinez., et al.: Development, 6, 851 (2002); Nakayama, K., et al.: J. Biochem., 146, 757 (2009); Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2009)

Formula: C₂CH₃O₃·Na

Color and Shape: Off White

Molecular weight: 112.03

Ref: TR-P998906