CAS 892-48-8

5′-Chloro-5′-deoxyadenosine

Description:

5′-Chloro-5′-deoxyadenosine is a nucleoside analog characterized by the presence of a chlorine atom at the 5' position of the deoxyribose sugar, replacing the hydroxyl group typically found in adenosine. This modification imparts unique biochemical properties, making it of interest in various fields, including medicinal chemistry and molecular biology. The compound is known for its potential antiviral and anticancer activities, as it can interfere with nucleic acid synthesis and cellular processes. Its structure consists of a purine base (adenine) linked to a deoxyribose sugar, which is further modified by the chlorine substitution. The presence of the chlorine atom can influence the compound's solubility, stability, and interaction with biological targets. 5′-Chloro-5′-deoxyadenosine is often utilized in research to study nucleoside metabolism and the mechanisms of action of nucleoside analogs in therapeutic applications. As with many nucleoside analogs, careful consideration of its pharmacokinetics and toxicity is essential for its potential use in clinical settings.

Formula: C₁₀H₁₂ClN₅O₃

InChI: InChI=1S/C10H12ClN5O3/c11-1-4-6(17)7(18)10(19-4)16-3-15-5-8(12)13-2-14-9(5)16/h2-4,6-7,10,17-18H,1H2,(H2,12,13,14)/t4-,6-,7-,10-/m1/s1

InChI key: InChIKey=IYSNPOMTKFZDHZ-KQYNXXCUSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CCl)[C@H]1O

Synonyms:

• 5'-Chloro-5'-Deoxyadenosine
• 5'-Chloro-5'-deoxyadenosin
• 5′-Deoxy-5′-chloroadenosine
• 9H-purin-6-amine, 9-(5-chloro-5-deoxypentofuranosyl)-
• Adenosine, 5'-Chloro-5'-Deoxy-

5'-Chloro-5'-deoxyadenosine

CAS: 892-48-8

Formula: C₁₀H₁₂ClN₅O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 285.69

Ref: 3B-C3773

5'-Chloro-5'-deoxyadenosine

CAS: 892-48-8

Formula: C₁₀H₁₂ClN₅O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 285.6870

Ref: IN-DA00425T

Ribavirin Impurity 63

CAS: 892-48-8

Formula: C₁₀H₁₂ClN₅O₃

Color and Shape: Off-White Solid

Molecular weight: 285.69

Ref: 4Z-R-0472

5'-Chloro-5'-deoxyadenosine

CAS: 892-48-8

5'-Chloro-5'-deoxyadenosine

Purity: 98%

Molecular weight: 285.69g/mol

Ref: 54-OR1011855

5''-Chloro-5''-deoxyadenosine

CAS: 892-48-8

Ref: 7W-GN5056

5'-Chloro-5'-deoxyadenosine

CAS: 892-48-8

Adenosine analog

Formula: C₁₀H₁₂ClN₅O₃

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 285.69 g/mol

Ref: 3D-NC05644

5'-Chloro-5'-deoxyadenosine

CAS: 892-48-8

Please enquire for more information about 5'-Chloro-5'-deoxyadenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₀H₁₂ClN₅O₃

Purity: Min. 98.0 Area-%

Molecular weight: 285.69 g/mol

Ref: 3D-J-700374

5′-Chloro-5′-deoxyadenosine

CAS: 892-48-8

Formula: C₁₀H₁₂ClN₅O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 285.69

Ref: 10-F463329

5'-Deoxy-5'-chloroadenosine

CAS: 892-48-8

Applications 5'-Deoxy-5'-chloroadenosine is an intermediate in the synthesis of 5'-Deoxy-5'-(methylthio)adenosine (D242600), a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways.
References Olopade, O., et al.: Cancer Res., 53, 2410 (1993), Hartmann, S., et al.: Clin. Chem., 52, 1127 (2006), Penner, N., et al.: J. Pharm. Biomed. Anal., 52, 534 (2010),

Formula: C₁₀H₁₂ClN₅O₃

Color and Shape: Neat

Molecular weight: 285.687

Ref: TR-D232545

Ribavirin Impurity 63

CAS: 892-48-8

Formula: C₁₀H₁₂ClN₅O₃

Molecular weight: 285.69

Ref: ST-EA-CP-R81011