CAS 892128-60-8

2′-Deoxy-2′,2′-difluoro-N-(1-oxo-2-propylpentyl)cytidine

Description:

2′-Deoxy-2′,2′-difluoro-N-(1-oxo-2-propylpentyl)cytidine is a synthetic nucleoside analog, characterized by the presence of two fluorine atoms at the 2′ position of the deoxyribose sugar, which enhances its stability and bioactivity. This compound is designed to mimic the natural nucleoside cytidine, with modifications that potentially improve its pharmacological properties, such as increased resistance to nucleases and enhanced antiviral activity. The presence of the N-(1-oxo-2-propylpentyl) side chain suggests that it may interact with specific biological targets, possibly influencing its efficacy in therapeutic applications. The structural modifications aim to optimize its performance in inhibiting viral replication or other cellular processes. As a nucleoside analog, it may be of interest in the development of antiviral therapies or in research related to nucleic acid metabolism. Its unique chemical structure and properties make it a subject of study in medicinal chemistry and drug development.

Formula: C₁₇H₂₅F₂N₃O₅

InChI: InChI=1S/C17H25F2N3O5/c1-3-5-10(6-4-2)14(25)20-12-7-8-22(16(26)21-12)15-17(18,19)13(24)11(9-23)27-15/h7-8,10-11,13,15,23-24H,3-6,9H2,1-2H3,(H,20,21,25,26)/t11-,13-,15-/m1/s1

InChI key: InChIKey=MEOYFIHNRBNEPI-UXIGCNINSA-N

SMILES: FC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(C(CCC)CCC)=O)C=C2

Synonyms:

• LY 2334737
• 2′-Deoxy-2′,2′-difluoro-N-(1-oxo-2-propylpentyl)cytidine
• Cytidine, 2′-deoxy-2′,2′-difluoro-N-(1-oxo-2-propylpentyl)-
• LY 2334737;LY-2334737;LY2334737
• Cytidine, 2'-deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)-
• LY2334737
• 2'-Deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)cytidine

LY2334737

CAS: 892128-60-8

Formula: C₁₇H₂₅F₂N₃O₅

Purity: 98.88%

Molecular weight: 389.3943

Ref: IN-DA00GU44

LY2334737

CAS: 892128-60-8

LY2334737

Purity: ≥98%

Molecular weight: 389.39g/mol

Ref: 54-BUP05192

LY2334737

CAS: 892128-60-8

LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.

Formula: C₁₇H₂₅F₂N₃O₅

Purity: 98.82%

Color and Shape: Solid

Molecular weight: 389.39

Ref: TM-T4061

LY 2334737

CAS: 892128-60-8

Orally available prodrug of gemcitabine

Formula: C₁₇H₂₅F₂N₃O₅

Purity: Min. 95%

Color and Shape: White To Yellow Solid

Molecular weight: 389.39 g/mol

Ref: 3D-BL98401