CAS 89213-87-6

Carperitide

Description:

Carperitide, with the CAS number 89213-87-6, is a synthetic peptide that functions primarily as a vasodilator. It is derived from the amino acid sequence of the endogenous peptide angiotensin II and is utilized in clinical settings, particularly in the treatment of heart failure and other cardiovascular conditions. Carperitide works by promoting the relaxation of blood vessels, thereby reducing systemic vascular resistance and improving cardiac output. Its mechanism of action involves the modulation of nitric oxide pathways, leading to enhanced blood flow and reduced myocardial oxygen demand. The substance is typically administered intravenously and is characterized by a relatively short half-life, necessitating careful monitoring during treatment. As with many pharmacological agents, potential side effects may include hypotension, headache, and gastrointestinal disturbances. Overall, Carperitide represents a valuable therapeutic option in managing acute heart failure, contributing to improved patient outcomes in critical care settings.

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

InChI: InChI=1/C127H203N45O39S3/c1-9-64(6)99-121(209)150-52-94(182)151-65(7)100(188)155-76(34-35-91(129)179)109(197)167-85(56-174)104(192)149-53-96(184)153-78(43-62(2)3)102(190)148-54-97(185)154-89(119(207)164-82(48-92(130)180)114(202)169-86(57-175)116(204)163-81(46-67-23-14-11-15-24-67)113(201)158-73(27-18-39-143-125(135)136)107(195)166-84(122(210)211)47-68-30-32-69(178)33-31-68)60-213-214-61-90(171-118(206)88(59-177)170-117(205)87(58-176)168-108(196)74(28-19-40-144-126(137)138)156-106(194)72(26-17-38-142-124(133)134)157-112(200)79(44-63(4)5)161-101(189)70(128)55-173)120(208)162-80(45-66-21-12-10-13-22-66)103(191)147-50-93(181)146-51-95(183)152-71(25-16-37-141-123(131)132)105(193)160-77(36-42-212-8)110(198)165-83(49-98(186)187)115(203)159-75(111(199)172-99)29-20-41-145-127(139)140/h10-15,21-24,30-33,62-65,70-90,99,173-178H,9,16-20,25-29,34-61,128H2,1-8H3,(H2,129,179)(H2,130,180)(H,146,181)(H,147,191)(H,148,190)(H,149,192)(H,150,209)(H,151,182)(H,152,183)(H,153,184)(H,154,185)(H,155,188)(H,156,194)(H,157,200)(H,158,201)(H,159,203)(H,160,193)(H,161,189)(H,162,208)(H,163,204)(H,164,207)(H,165,198)(H,166,195)(H,167,197)(H,168,196)(H,169,202)(H,170,205)(H,171,206)(H,172,199)(H,186,187)(H,210,211)(H4,131,132,141)(H4,133,134,142)(H4,135,136,143)(H4,137,138,144)(H4,139,140,145)/t64-,65-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,99-/m0/s1

SMILES: CC[C@H](C)[C@H]1C(=NCC(=N[C@@H](C)C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CO)C(=NCC(=N[C@@H](CC(C)C)C(=NCC(=N[C@@H](CSSC[C@@H](C(=N[C@@H](Cc2ccccc2)C(=NCC(=NCC(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](CCSC)C(=N[C@@H](CC(=O)O)C(=N[C@@H](CCCNC(=N)N)C(=N1)O)O)O)O)O)O)O)O)N=C([C@H](CO)N=C([C@H](CO)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](CO)N)O)O)O)O)O)O)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CO)C(=N[C@@H](Cc1ccccc1)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](Cc1ccc(cc1)O)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O

Synonyms:

• Atrial natriuretic factor (99-126)
• Atriopeptin-28 (human)
• Ccris 4930
• Human atriopeptin(1-28)
• Human atriopeptin(99-126)
• L-Seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine cyclic(7-23)-disulfide
• Sun-4936
• Triopeptin (human alpha-component)
• alpha-Atriopeptin (human)
• alpha-Human atrial natriuretic hormone
• alpha-Human atriopeptin
• Atriopeptin-33(rat), 1-de-L-leucine-2-de-L-alanine-3-deglycine-4-de-L-proline-5-de-L-arginine-17-L-methionine-
• alpha-Atriopeptin
• Anp 1-28, Human
• Carperitide Acetate
• α-Atrial natriuretic peptide human recombinant

Atrial Natriuretic Factor (1-28) (human)

CAS: 89213-87-6

Bachem ID: 4095851.

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Color and Shape: White

Molecular weight: 3080.49

Ref: 01-4095851

Atrial Natriuretic Factor (1-28) (human)

CAS: 89213-87-6

ANP/ANF is synthesized in cardiac myocytes and is primarily released in response to atrial wall stretching and intravascular volume expansion. The peptide signals via the guanylate cyclase-linked natriuretic peptide receptor A (NPR-A) and plays an important role in blood pressure regulation and blood volume homeostasis. ANP/ANF exerts vasodilatory, diuretic, natriuretic, anti-inflammatory, antifibrotic and antimitogenic effects. As BNP, ANP stimulates lipolysis in adipocytes. Millucci et al. studied the aggregation behavior of αANP, which may play a role in congestive heart failure.

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Purity: 97.80%

Color and Shape: White

Molecular weight: 3080.49

Ref: 01-4011941

Atrial Natriuretic Factor (1-28) (human)

CAS: 89213-87-6

Bachem ID: 4092396.

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Purity: 98.2%

Color and Shape: White

Molecular weight: 3080.49

Ref: 01-4092396

ANP 1-28, HUMAN

CAS: 89213-87-6

Formula: C₁₂₉H₂₀₄F₃N₄₅O₄₁S₃

Purity: 95%

Molecular weight: 3194.4672

Ref: IN-DA00GS7B

Carperitide Acetate

CAS: 89213-87-6

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 3080.44

Ref: BP-BPPG015

Atrial Natriuretic Factor (1-28)

CAS: 89213-87-6

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Molecular weight: 3,080.46 g/mol

Ref: 3D-PP50497

Atrial Natriuretic Factor (1-28) (human) hydrochloride salt

Controlled Product

CAS: 89213-87-6

Please enquire for more information about Atrial Natriuretic Factor (1-28) (human) hydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Purity: Min. 95%

Molecular weight: 3,080.45 g/mol

Ref: 3D-FA110233