CAS 892549-43-8

MF-63

CAS: 892549-43-8

Formula: C₂₃H₁₁ClN₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 378.8132

Ref: IN-DA00GTCB

MF63

CAS: 892549-43-8

MF63 is a selective mPGES-1 inhibitor (IC50: 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively).

Formula: C₂₃H₁₁ClN₄

Color and Shape: Solid

Molecular weight: 378.81

Ref: TM-T16070

MF 63

CAS: 892549-43-8

MF 63 is an anti-inflammatory drug that blocks the action of prostaglandin E2 (PGE2). It is used to treat chronic arthritis and inflammatory diseases, such as Crohn's disease. MF 63 has been shown to inhibit nitrite reductase activity in a type strain from Pseudomonas aeruginosa. This enzyme catalyzes the conversion of nitrite to nitric oxide, which is involved in regulating cell growth and proliferation. The drug also inhibits epidermal growth factor-induced tyrosine phosphorylation and cellular proliferation in cultured human keratinocytes. MF 63 has also been shown to inhibit the growth of tumor cells derived from chronic lymphocytic leukemia and colon cancer cells.

Formula: C₂₃H₁₁ClN₄

Purity: Min. 95%

Molecular weight: 378.81 g/mol

Ref: 3D-SKB54943