CAS 89292-78-4

1-(2-fluorobenzyl) piperazine

Description:

1-(2-Fluorobenzyl) piperazine is an organic compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. The presence of a 2-fluorobenzyl group attached to the piperazine ring significantly influences its chemical properties and biological activity. This compound typically exhibits a white to off-white crystalline appearance and is soluble in polar organic solvents. Its molecular structure allows for potential interactions with various biological targets, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The fluorine atom in the benzyl group can enhance lipophilicity and metabolic stability, which may affect the compound's pharmacokinetics. Additionally, 1-(2-fluorobenzyl) piperazine may exhibit psychoactive properties, as many piperazine derivatives are known to interact with neurotransmitter systems. Safety and handling precautions should be observed, as with any chemical substance, due to potential toxicity and reactivity. Overall, this compound serves as a valuable scaffold in drug discovery and development.

Formula: C₁₁H₁₅FN₂

InChI: InChI=1/C11H15FN2/c12-11-4-2-1-3-10(11)9-14-7-5-13-6-8-14/h1-4,13H,5-9H2

SMILES: c1ccc(c(c1)CN1CCNCC1)F

Synonyms:

• Piperazine, 1-[(2-fluorophenyl)methyl]-
• 1-(2-Fluorobenzyl)piperazine
• 1-(2-FLUOROBENYL)-PIPERAZINE
• TIMTEC-BB SBB003603
• BUTTPARK 37\08-27
• ART-CHEM-BB B004013
• 1-(2-FLUORO-BENZYL)-PIPERAZINE DIHYDROCHLORIDE
• AKOS B004013

1-(2-Fluorobenzyl)piperazine

CAS: 89292-78-4

Formula: C₁₁H₁₅FN₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 194.2486

Ref: IN-DA0087FD

1-(2-Fluorobenzyl)piperazine

Controlled Product

CAS: 89292-78-4

1-(2-Fluorobenzyl)piperazine (1FP) is an inhibitor of cholinesterase, which is an enzyme that breaks down the neurotransmitter acetylcholine. It binds to the active site of the enzyme and prevents it from functioning. 1FP has a high affinity for benzylpiperazine (BZP), but lower affinity for phenylpiperazine (PP). The conformational kinetic study showed that 1FP inhibits BZP more effectively than PP. This is due to the fact that 1FP has a higher dihedral angle, making it more likely to bind in the active site of BZP.

Purity: Min. 95%

Ref: 3D-FF38087