CAS 89371-37-9

Imidapril

Description:

Imidapril is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It functions by inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. The chemical formula of Imidapril is C20H28N2O5S, and it features a unique structure that includes an imidazole ring, which contributes to its pharmacological activity. Imidapril is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include dizziness, cough, and elevated potassium levels, similar to other ACE inhibitors. It is important to monitor renal function and electrolyte levels during treatment. Imidapril is often prescribed in combination with other antihypertensive agents to enhance therapeutic efficacy. As with all medications, it is crucial to use Imidapril under the guidance of a healthcare professional to ensure safety and effectiveness.

Formula: C₂₀H₂₇N₃O₆

InChI: InChI=1S/C20H27N3O6/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26)/t13-,15-,16-/m0/s1

InChI key: InChIKey=KLZWOWYOHUKJIG-BPUTZDHNSA-N

SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CN(C)C2=O

Synonyms:

• (4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid
• (4S)-3-{N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl}-1-methyl-2-oxoimidazolidine-4-carboxylic acid
• (4S)-3-{N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl}-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride
• (4S)-3-{N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1-methyl-2-oxoimidazolidine-4-carboxylic acid
• 4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-
• 4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, [4R-[3[R*(R*)],4R*]]-
• 4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, [4S-[3[R*(R*)],4R*]]-
• 4-imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, (4S)-
• Tanatril
• [4S-[3[R*(R*)],4R*]]-3-[2-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropil]-1-methyl-2-oxo-4-imidazolinecarboxylic Acid
• Imidapril

Imidapril Hydrochloride

CAS: 89371-37-9

Formula: C₂₀H₂₇N₃O₆

Purity: 97%

Molecular weight: 405.4449

Ref: IN-DA003YVV

Imidapril-d5 HCl

CAS: 89371-37-9

Formula: C₂₀H₂₂D₅N₃O₆·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 410.48 36.46

Ref: 4Z-I-143

Imidapril

CAS: 89371-37-9

Formula: C₂₀H₂₇N₃O₆

Molecular weight: 405.44

Ref: 7W-GP9204

Imidapril Hydrochloride

CAS: 89371-37-9, 89396-94-1

Formula: C₂₀H₂₇N₃O₆·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 441.91

Ref: 3B-I0901

Imidapril

CAS: 89371-37-9

Imidapril: oral ACE & MMP-9 inhibitor, lowers blood pressure, useful in hypertension, diabetic nephropathy, heart failure.

Formula: C₂₀H₂₇N₃O₆

Color and Shape: Solid

Molecular weight: 405.44

Ref: TM-T62005