CymitQuimica logo

CAS 89396-94-1

:

Imidapril hydrochloride

Description:
Imidapril hydrochloride is an antihypertensive medication primarily used to treat high blood pressure and heart failure. It belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. The chemical structure of imidapril hydrochloride features a unique imidazole ring, which contributes to its pharmacological activity. As a prodrug, it is converted in the body to its active form, imidaprilat, which inhibits the ACE enzyme, leading to decreased production of angiotensin II, a potent vasoconstrictor. This results in vasodilation, reduced blood pressure, and decreased workload on the heart. Imidapril hydrochloride is typically administered orally and is well-absorbed, with a relatively long half-life allowing for once-daily dosing. Common side effects may include dizziness, cough, and elevated potassium levels. It is contraindicated in patients with a history of angioedema related to previous ACE inhibitor therapy and should be used cautiously in those with renal impairment. Overall, imidapril hydrochloride is an effective option in managing hypertension and related cardiovascular conditions.
Formula:C20H27N3O6
InChI:InChI=1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
InChI key:InChIKey=LSLQGMMMRMDXHN-GEUPQXMHSA-N
SMILES:C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CN(C)C2=O.Cl
Synonyms:
  • (-)-3-[N-[1(S)-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4(S)-carboxylic acid hydrochloride
  • (S)-3-[(S)-2-((S)-1-Ethoxycarbonyl-3-Phenyl-Propylamino)-Propionyl]-1-Methyl-2-Oxo-Imidazolidine-4-Carboxylic Acid Hydrochloride
  • 4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, hydrochloride (1:1), (4S)-
  • 4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, monohydrochloride, (4S)-
  • 4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, monohydrochloride, [4S-[3[R*(R*)],4R*]]-
  • Imidapril HCl
  • Imidapril hydrochloride
  • Novaloc
  • Novarok
  • Sh-6366
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.