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CAS 894-71-3

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Nortriptyline hydrochloride

Description:
Nortriptyline hydrochloride is a tricyclic antidepressant primarily used to treat major depressive disorder and certain types of chronic pain. It functions by inhibiting the reuptake of neurotransmitters, particularly norepinephrine and serotonin, thereby enhancing mood and alleviating pain. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration in tablet form or as a liquid. Its chemical formula is C19H21N·HCl, indicating the presence of a hydrochloride salt, which enhances its stability and solubility. Nortriptyline hydrochloride has a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include dry mouth, drowsiness, and weight gain, while more serious risks involve cardiovascular effects and potential for overdose. Due to its pharmacological profile, it is essential for patients to be monitored for efficacy and adverse reactions during treatment. As with all medications, it should be used under the guidance of a healthcare professional.
Formula:C19H21N·ClH
InChI:InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H
InChI key:InChIKey=SHAYBENGXDALFF-UHFFFAOYSA-N
SMILES:C(CCNC)=C1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:
  • 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride
  • 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride (1:1)
  • 10,11-Dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ<sup>5,γ</sup>-propylamine hydrochloride
  • 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-aminium chloride
  • 38489
  • 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene hydrochloride
  • 5-[3-(Methylamino)propylidene]dibenzo[a,e]cyclohepta[1,5]diene hydrochloride
  • 5H-Dibenzo[a,d]cycloheptene-Δ<sup>5,γ</sup>-propylamine, 10,11-dihydro-N-methyl-, hydrochloride
  • Acetexa
  • Allegron
  • See more synonyms
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