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CAS 89468-62-2

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Helodermin

Description:
Helodermin is a peptide that is derived from the venom of the Heloderma species, specifically the Gila monster. It is characterized by its structure, which includes a sequence of amino acids that contribute to its biological activity. Helodermin is known for its ability to bind to specific receptors in the body, particularly those involved in glucose metabolism, making it of interest in diabetes research. The substance exhibits properties similar to those of insulin, influencing glucose uptake and potentially offering therapeutic benefits for managing blood sugar levels. Additionally, Helodermin has been studied for its neuroprotective effects and potential applications in treating neurodegenerative diseases. Its unique origin and biological functions make it a subject of interest in pharmacological studies, although further research is necessary to fully understand its mechanisms and potential clinical applications. As with many peptides, stability and delivery methods are key considerations in its therapeutic use.
Formula:C176H285N47O49
Synonyms:
  • HELODORMIN
  • heliodermin
  • VASOACTIVE INTESTINAL PEPTIDE-PHI LIKE PEPTIDE
  • HIS-SER-ASP-ALA-ILE-PHE-THR-GLN-GLN-TYR-SER-LYS-LEU-LEU-ALA-LYS-LEU-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
  • H-HIS-SER-ASP-ALA-ILE-PHE-THR-GLU-GLU-TYR-SER-LYS-LEU-LEU-ALA-LYS-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
  • HELODERMIN (HELODERMA SUSPECTUM)
  • H-HIS-SER-ASP-ALA-ILE-PHE-THR-GLN-GLN-TYR-SER-LYS-LEU-LEU-ALA-LYS-LEU-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
  • HIS-SER-ASP-ALA-ILE-PHE-THR-GLU-GLU-TYR-SER-LYS-LEU-LEU-ALA-LYS-LEU-ALA-LEU-GLN-LYS-TYR-LEU-ALA-SER-ILE-LEU-GLY-SER-ARG-THR-SER-PRO-PRO-PRO-NH2
  • HSDAIFTQQYSKLLAKLALQKYLASILGSRTSPPP
  • H-His-Ser-Asp-Ala-Ile-Phe-Thr-Glu-Glu-Tyr-Ser-Lys-Leu-Leu-Ala-Lys-Leu-Ala-Leu-Gln-Lys-Tyr-Leu-Ala-Ser-Ile-Leu-Gly-Ser-Arg-Thr-Ser-Pro-Pro-Pro-NH2
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