CAS 89499-17-2

(8E,24E)-5,6,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-({[4-(2-methylpropyl)piperazin-1-yl]amino}methylidene)-1,9,11-trioxo-1,2,8,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate

Description:

The chemical substance with the name "(8E,24E)-5,6,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-({[4-(2-methylpropyl)piperazin-1-yl]amino}methylidene)-1,9,11-trioxo-1,2,8,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate" and CAS number "89499-17-2" is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as hydroxyl (-OH), methoxy (-OCH3), and amine (-NH) groups. This compound features a naphtho-furan backbone, indicating potential aromatic properties, and contains several methyl groups that contribute to its hydrophobic characteristics. The presence of epoxide and trioxo functionalities suggests reactivity that could be exploited in synthetic applications or biological interactions. Additionally, the piperazine moiety may impart specific pharmacological properties, making this compound of interest in medicinal chemistry. Its stereochemistry, indicated by the E configuration, suggests specific spatial arrangements that could influence its biological activity and interactions with other molecules. Overall, this substance exemplifies the complexity often found in bioactive compounds, with potential implications in drug development and therapeutic applications.

Formula: C₄₆H₆₄N₄O₁₂

InChI: InChI=1/C46H64N4O12/c1-23(2)22-49-16-18-50(19-17-49)47-21-31-36-41(56)34-33(40(31)55)35-43(29(8)39(34)54)62-46(10,44(35)57)60-20-15-32(59-11)26(5)42(61-30(9)51)28(7)38(53)27(6)37(52)24(3)13-12-14-25(4)45(58)48-36/h12-15,20-21,23-24,26-28,32,37-38,42,47,52-54,56H,16-19,22H2,1-11H3,(H,48,58)/b13-12+,20-15+,25-14+,31-21+

Rifamdin-d4

Controlled Product

CAS: 89499-17-2

Formula: C₄₆H₆₀D₄N₄O₁₂

Color and Shape: Neat

Molecular weight: 869.06

Ref: TR-R507902

Rifamdin-d9

Controlled Product

CAS: 89499-17-2

Formula: C₄₆H₅₅D₉N₄O₁₂

Color and Shape: Neat

Molecular weight: 874.08

Ref: TR-R507903

Rifamdin

Controlled Product

CAS: 89499-17-2

Stability Hygroscopic, Light Sensitive
Applications A Rifamicyn derivative with therapeutic effect on pulmonary tuberculosis.
References Gozalbes, R., et al.: J. Pharm. Pharmacol., 51, 111 (1999), Estrada, E., et al.: J. Med. Chem., 43, 1975 (2000), Gonzalez-Diaz, H., et al.: Chem. Res. Toxicol., 16, 1318 (2003), Garcia-Garcia, A., et al.: J. Antimicrob. Chemother., 53, 65 (2004),

Formula: C₄₅H₆₃N₃O₁₂

Color and Shape: Neat

Molecular weight: 837.99

Ref: TR-R507900

Rifamdin

CAS: 89499-17-2

Rifamdin is an antibiotic, which is a chemical substance derived from the source compound rifampicin. Its mode of action involves the inhibition of bacterial DNA-dependent RNA polymerase, which effectively suppresses bacterial RNA synthesis, leading to cell death. This mechanism primarily targets Mycobacterium tuberculosis, the causative agent of tuberculosis.

Formula: C₄₆H₆₄N₄O₁₂

Purity: Min. 95%

Molecular weight: 865.02 g/mol

Ref: 3D-AR27728