CAS 89565-68-4

Tropisetron

Description:

Tropisetron is a chemical compound classified as a selective serotonin 5-HT3 receptor antagonist, primarily used in the management of nausea and vomiting associated with chemotherapy and surgery. It is characterized by its ability to inhibit the action of serotonin at the 5-HT3 receptor sites, which are involved in the vomiting reflex. Tropisetron is typically administered orally or intravenously and has a relatively long half-life, allowing for effective control of symptoms over extended periods. The compound is known for its favorable pharmacokinetic profile, including good oral bioavailability. In terms of its chemical structure, Tropisetron features a piperidine ring and a substituted indole moiety, contributing to its biological activity. It is important to note that, like other medications, Tropisetron may have side effects, including headache, constipation, and dizziness. Overall, its efficacy in preventing chemotherapy-induced nausea and vomiting has made it a valuable option in clinical settings.

Formula: C₁₇H₂₀N₂O₂

InChI: InChI=1/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+

InChI key: InChIKey=ZNRGQMMCGHDTEI-ITGUQSILNA-N

SMILES: C(O[C@H]1C[C@@]2(N(C)[C@](C1)(CC2)[H])[H])(=O)C=3C=4C(NC3)=CC=CC4

Synonyms:

• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate
• (1S,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate
• 1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
• 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-
• Ics 205-930
• Ics 205930
• Navoban
• Tropisetron

Tropisetron

CAS: 89565-68-4

Formula: C₁₇H₂₀N₂O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 284.3529

Ref: IN-DA003Y8P

Tropisetron

CAS: 89565-68-4

Tropisetron

Purity: 99%

Molecular weight: 284.35g/mol

Ref: 54-OR1027083

Tropisetron

CAS: 89565-68-4

Tropisetron

Purity: ≥98%

Molecular weight: 284.35g/mol

Ref: 54-BUP11110

Tropisetron

CAS: 89565-68-4

Formula: C₁₇H₂₀N₂O₂

Molecular weight: 284.35

Ref: 7W-GP7589

Tropisetron Hydrochloride

CAS: 105826-92-4, 89565-68-4

Formula: C₁₇H₂₀N₂O₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 320.82

Ref: 3B-T2743

Tropisetron

CAS: 89565-68-4

Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.

Formula: C₁₇H₂₀N₂O₂

Purity: 99.68%

Color and Shape: White Solid

Molecular weight: 284.35

Ref: TM-T22448