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CAS 89662-30-6

:

Detirelix

Description:
Detirelix, with the CAS number 89662-30-6, is a synthetic peptide that functions as a gonadotropin-releasing hormone (GnRH) antagonist. It is primarily used in the field of reproductive medicine, particularly for its role in controlling hormone levels during assisted reproductive technologies. The substance works by competitively inhibiting the GnRH receptors in the pituitary gland, leading to a decrease in the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This action helps to prevent premature ovulation and allows for better timing of ovulation induction. Detirelix is characterized by its high specificity and potency, making it an effective tool in managing fertility treatments. Additionally, it is typically administered via subcutaneous injection. As with many pharmaceuticals, the use of Detirelix may be associated with side effects, which can include reactions at the injection site, headaches, and gastrointestinal disturbances. Overall, Detirelix plays a significant role in enhancing the success rates of fertility treatments by providing better control over hormonal fluctuations.
Formula:C78H105ClN18O13
InChI:InChI=1/C78H105ClN18O13/c1-7-83-78(84-8-2)86-34-14-13-21-58(68(102)92-60(37-45(3)4)69(103)91-59(22-15-35-85-77(81)82)76(110)97-36-16-23-66(97)75(109)88-46(5)67(80)101)90-71(105)62(40-49-27-32-55(100)33-28-49)94-74(108)65(44-98)96-73(107)64(42-53-43-87-57-20-12-11-19-56(53)57)95-72(106)63(39-48-25-30-54(79)31-26-48)93-70(104)61(89-47(6)99)41-50-24-29-51-17-9-10-18-52(51)38-50/h9-12,17-20,24-33,38,43,45-46,58-66,87,98,100H,7-8,13-16,21-23,34-37,39-42,44H2,1-6H3,(H2,80,101)(H,88,109)(H,89,99)(H,90,105)(H,91,103)(H,92,102)(H,93,104)(H,94,108)(H,95,106)(H,96,107)(H4,81,82,85)(H2,83,84,86)/t46-,58-,59+,60+,61-,62+,63-,64-,65+,66+/m1/s1
Synonyms:
  • N-Acetyl-3-(2-naphthyl)-D-alanyl-p-chloro-D-phenylalanyl-D-tryptophyl-L-seryl-L-tyrosyl-N(sup 6)-(N,N'-diethylamidino)-D-lysyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide
  • Detirelixum [Latin]
  • N-Ac-D-Nal(2)1,D-pCl-Phe2,D-Trp3,D-hArg(Et2)6,D-Ala(10)-GnRH
  • BRN 6564671
  • Detirelix [USAN]
  • Detirelixum
  • D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-D-tryptophyl-L-seryl-L-tyrosyl-N(sup 6)-(bis(ethylamino)methylene)-D-lysyl-L-leucyl-L-arginyl-L-prolyl-
  • D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-D-tryptophyl-L-seryl-L-tyrosyl-N6-(bis(ethylamino)methylene)-D-lysyl-L-leucyl-L-arginyl-L-prolyl-
  • Deterelix
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