CAS 896736-21-3

2-hydroxy-N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e]benzofuran-8-yl]ethyl]propanamide

Description:

2-hydroxy-N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e]benzofuran-8-yl]ethyl]propanamide, with the CAS number 896736-21-3, is a synthetic organic compound characterized by its complex structure, which includes a hydroxy group, an amide functional group, and a bicyclic system derived from cyclopenta[e]benzofuran. This compound features a chiral center, indicated by the (8S) configuration, which contributes to its stereochemical properties and potential biological activity. The presence of the hydroxy group suggests it may exhibit hydrogen bonding capabilities, influencing its solubility and reactivity. The bicyclic structure may impart unique pharmacological properties, making it of interest in medicinal chemistry. Additionally, the compound's amide linkage can affect its stability and interactions with biological targets. Overall, this substance may be explored for its potential applications in drug development, particularly in areas related to neuropharmacology or other therapeutic fields, although specific biological activities would require further investigation.

Formula: C₁₆H₂₁NO₃

InChI: InChI=1/C16H21NO3/c1-10(18)16(19)17-8-6-12-3-2-11-4-5-14-13(15(11)12)7-9-20-14/h4-5,10,12,18H,2-3,6-9H2,1H3,(H,17,19)/t10?,12-/m0/s1

SMILES: CC(C(=NCC[C@@H]1CCc2ccc3c(CCO3)c12)O)O

(R,S)-hydroxy Ramelteon Metabolite M-II

CAS: 896736-21-3

Formula: C₁₆H₂₁NO₃

Color and Shape: Solid

Molecular weight: 275.3428

Ref: IN-DA0043SF

Ramelteon metabolite M-II

CAS: 896736-21-3

Ramelteon M-II binds MT1/MT2 with IC50s: 208/1470 pM; it's the main metabolite and a melatonin receptor agonist.

Formula: C₁₆H₂₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 275.34

Ref: TM-T12689

Ramelteon Metabolite M-II

CAS: 896736-21-3

Formula: C₁₆H₂₁NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 275.35

Ref: 4Z-R-153

Ramelteon Metabolite M-II (mixture of R and S at the hydroxy position)

Controlled Product

CAS: 896736-21-3

Applications The major metabolite of Ramelteon in serum (M-II).
References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004), Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004), Kato, K., et al.: Neuropharmacology, 48, 301 (2005), Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006),

Formula: C₁₆H₂₁NO₃

Color and Shape: Neat

Molecular weight: 275.34

Ref: TR-R110060

(R)-Ramelteon Metabolite M-II

Controlled Product

CAS: 896736-21-3

Applications R-Ramelteon Metabolite M-II is a metabolite of Ramelteon in serum (M-II).
References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004); Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004); Kato, K., et al.: Neuropharmacology, 48, 301 (2005); Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006)

Formula: C₁₁H₁₈O₄S

Color and Shape: Neat

Molecular weight: 246.323

Ref: TR-R110065