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CAS 897-15-4

:

Dothiepin hydrochloride

Description:
Dothiepin hydrochloride, also known as dosulepin, is a tricyclic antidepressant primarily used in the treatment of depression and anxiety disorders. It functions by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby enhancing mood and emotional stability. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Dothiepin hydrochloride has a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include sedation, dry mouth, and weight gain, which are typical of tricyclic antidepressants. Due to its potential for overdose and interactions with other medications, careful monitoring is essential during treatment. Additionally, it is important to consider contraindications, such as pre-existing heart conditions, when prescribing this medication. Overall, dothiepin hydrochloride remains a valuable option in the pharmacological management of mood disorders, particularly in patients who may not respond to other classes of antidepressants.
Formula:C19H21NS·ClH
InChI:InChI=1S/C19H21NS.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H
InChI key:InChIKey=XUPZAARQDNSRJB-UHFFFAOYSA-N
SMILES:C(CCN(C)C)=C1C=2C(CSC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:
  • (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-aminium chloride
  • (3Z)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-aminium chloride
  • 1-Propanamine, 3-(dibenzo[b,e]thiepin-11(6H)-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
  • 1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride
  • 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]thiepin hydrochloride
  • 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
  • Altapin
  • Depresym
  • Dibenzo[b,e]thiepin, 1-propanamine deriv.
  • Dibenzo[b,e]thiepin-Δ<sup>11(6</sup><sup>H</sup><sup>),γ</sup>-propylamine, N,N-dimethyl-, hydrochloride
  • See more synonyms
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Found 15 products.