CAS 897-15-4
:Dothiepin hydrochloride
Description:
Dothiepin hydrochloride, also known as dosulepin, is a tricyclic antidepressant primarily used in the treatment of depression and anxiety disorders. It functions by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby enhancing mood and emotional stability. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Dothiepin hydrochloride has a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include sedation, dry mouth, and weight gain, which are typical of tricyclic antidepressants. Due to its potential for overdose and interactions with other medications, careful monitoring is essential during treatment. Additionally, it is important to consider contraindications, such as pre-existing heart conditions, when prescribing this medication. Overall, dothiepin hydrochloride remains a valuable option in the pharmacological management of mood disorders, particularly in patients who may not respond to other classes of antidepressants.
Formula:C19H21NS·ClH
InChI:InChI=1S/C19H21NS.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H
InChI key:InChIKey=XUPZAARQDNSRJB-UHFFFAOYSA-N
SMILES:C(CCN(C)C)=C1C=2C(CSC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:- (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-aminium chloride
- (3Z)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-aminium chloride
- 1-Propanamine, 3-(dibenzo[b,e]thiepin-11(6H)-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
- 1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride
- 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]thiepin hydrochloride
- 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
- Altapin
- Depresym
- Dibenzo[b,e]thiepin, 1-propanamine deriv.
- Dibenzo[b,e]thiepin-Δ<sup>11(6</sup><sup>H</sup><sup>),γ</sup>-propylamine, N,N-dimethyl-, hydrochloride
- Dosulepin chloride
- Dosulepin hydrochloride
- Dothiepin HCl
- Prothiaden hydrochloride
- See more synonyms
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Found 15 products.
Dothiepin Hydrochloride (Dosulepin Hydrochloride) 1.0 mg/ml in Methanol (as free base)
CAS:Color and Shape:ColourlessDosulepin hydrochloride
CAS:Dosulepin hydrochlorideFormula:C19H21NSHClPurity:100.0%Color and Shape:Light YellowMolecular weight:331.1161511-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]thiepin hydrochloride
CAS:Formula:C19H22ClNSPurity:95%Color and Shape:SolidMolecular weight:331.9027Dothiepin hydrochloride
CAS:Formula:C19H22ClNSPurity:≥ 98%Color and Shape:White to pale yellow powderMolecular weight:331.90Dothiepin hydrochloride
CAS:Controlled ProductFormula:C19H21NS·ClHColor and Shape:NeatMolecular weight:331.90Dothiepin hydrochloride - Bio-X ™
CAS:<p>Dothiepin is a tricyclic antidepressant used to treat depression in patients who are not responding to alternative therapies. This drug inhibits the reuptake of norepinephrine and serotonin, increasing available neurotransmitter levels at the synaptic cleft. It also exhibits anticholinergic, antihistamine and central sedative properties.</p>Formula:C19H21NS·HClPurity:Min. 98%Color and Shape:PowderMolecular weight:331.9 g/molDothiepin HCl
CAS:<p>Serotonin and norepinephrine reuptake inhibitor; tricyclic anti-depressant</p>Formula:C19H21NS·HClPurity:Min. 95%Color and Shape:White PowderMolecular weight:331.9 g/molDothiepin Hydrochloride
CAS:Controlled ProductFormula:C19H21NS·ClHColor and Shape:NeatMolecular weight:331.90










