CAS 89705-21-5

N-[2-(4-aminophenyl)ethyl]adenosine

Description:

N-[2-(4-aminophenyl)ethyl]adenosine, with the CAS number 89705-21-5, is a chemical compound that belongs to the class of adenosine derivatives. This substance features an adenosine backbone, which is a nucleoside composed of an adenine base attached to a ribose sugar. The distinguishing characteristic of this compound is the presence of a 4-aminophenyl ethyl group at the N-2 position of the ribose moiety, which contributes to its biological activity. The compound is known for its potential pharmacological properties, particularly in modulating adenosine receptors, which play a crucial role in various physiological processes, including neurotransmission and cardiovascular function. Its structure suggests that it may exhibit both hydrophilic and lipophilic characteristics, influencing its solubility and permeability in biological systems. As a result, N-[2-(4-aminophenyl)ethyl]adenosine may have applications in research related to neuropharmacology and therapeutic interventions targeting adenosine signaling pathways.

Formula: C₁₈H₂₂N₆O₄

InChI: InChI=1/C18H22N6O4/c19-11-3-1-10(2-4-11)5-6-20-16-13-17(22-8-21-16)24(9-23-13)18-15(27)14(26)12(7-25)28-18/h1-4,8-9,12,14-15,18,25-27H,5-7,19H2,(H,20,21,22)/t12-,14-,15-,18-/m1/s1

SMILES: c1cc(ccc1CCNc1c2c(ncn1)n(cn2)C1C(C(C(CO)O1)O)O)N

Synonyms:

• 9H-purin-6-amine, N-[2-(4-aminophenyl)ethyl]-9-pentofuranosyl-

APNEA

CAS: 89705-21-5

APNEA

Purity: ≥98%

Molecular weight: 386.41g/mol

Ref: 54-BUP14243

N6-2-(4-Aminophenyl)ethyladenosine

CAS: 89705-21-5

N6-2-(4-Aminophenyl)ethyladenosine is a carbamazepine prodrug that is converted to the active form, carbamazepine, by esterases. It has been shown to inhibit the binding of adenosine to adenosine receptor subtypes and to have an antagonistic effect on the activity of endogenous adenosine at these receptors. N6-2-(4-Aminophenyl)ethyladenosine has also been shown to act as an antagonist at the A3 adenosine receptor. This drug has been shown to reduce bronchoconstrictor responses in animal models and may be used for treating asthma.
N6-2-(4-Aminophenyl)ethyladenosine has also been shown in vitro studies using human papillary muscle cells to enhance polymerase chain reactions (PCR).

Purity: Min. 95%

Ref: 3D-NA72432

APNEA

CAS: 89705-21-5

APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) is a non-selective agonist of adenosine A3 receptor.

Formula: C₁₈H₂₂N₆O₄

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 386.41

Ref: TM-T12159