CAS 89778-27-8
:Toremifene citrate
Description:
Toremifene citrate is a selective estrogen receptor modulator (SERM) primarily used in the treatment of breast cancer, particularly in postmenopausal women. It functions by binding to estrogen receptors, thereby inhibiting the effects of estrogen on breast tissue, which can help slow or stop the growth of estrogen-dependent tumors. The compound is characterized by its chemical structure, which includes a triphenylethylene backbone, contributing to its ability to selectively modulate estrogen activity. Toremifene citrate is typically administered orally and is known for its relatively favorable side effect profile compared to other hormonal therapies. It may also exhibit some agonistic effects on bone and lipid metabolism, which can be beneficial in certain contexts. The substance is usually well-absorbed in the gastrointestinal tract, with metabolism primarily occurring in the liver. As with any medication, monitoring for potential side effects, such as hot flashes or thromboembolic events, is essential during treatment. Overall, Toremifene citrate represents an important therapeutic option in the management of hormone-sensitive breast cancer.
Formula:C26H28ClNO·C6H8O7
InChI:InChI=1S/C26H28ClNO.C6H8O7/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-16H,17-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;
InChI key:InChIKey=IWEQQRMGNVVKQW-OQKDUQJOSA-N
SMILES:C(=C(/CCCl)\C1=CC=CC=C1)(\C2=CC=C(OCCN(C)C)C=C2)/C3=CC=CC=C3.C(CC(O)=O)(CC(O)=O)(C(O)=O)O
Synonyms:- (Z)-2-[4-(4-Chloro-1,2-Diphenyl-1-Butenyl)Phenoxy]-N,N-Dimethyl-Ethanamine 2-Hydroxy-1,2,3-Propanetricarboxylate
- (Z)-4-Chloro-1,2-Diphenyl-1-(4-(2-(N,N-Dimethylamino)Ethoxy)Phenyl)-1-Butene
- 2-(4-(4-Chloro-1,2-Diphenyl-1-Butenyl)Phenoxy)-N,N-Dimethyl-Ethanamin(Z)-Ethanamin
- 2-Hydroxy-1,2,3-Propanetricarboxylate(1:1)
- 2-[4-[(1Z)-4-Chloro-1,2-Diphenyl-1-Butenyl]Phenoxy]-N,N-Dimethylethanamine
- Acapodene
- Ethanamine, 2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- Ethanamine, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- Ethanamine, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- FC 1157a
- Fareston
- Fc1157A
- GTx 006
- NSC 613680
- Nk 622
- Nk622
- Tropisetron Citrate
- Z-Toremifene
- Toremifene citrate
- See more synonyms
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Found 7 products.
Toremifene Citrate
CAS:Formula:C26H28ClNO·C6H8O7Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:598.09Toremifene Citrate
CAS:Formula:C26H28ClNO·C6H8O7Color and Shape:White To Off-White SolidMolecular weight:405.97 192.12Toremifene citrate
CAS:<p>Toremifene citrate is a selective estrogen receptor modulator (SERM). It is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on the mammary and uterine tissue.</p>Formula:C32H36ClNO8Purity:99.83% - >99.99%Color and Shape:White Or Almost White PowderMolecular weight:598.08Toremifene Citrate
CAS:Controlled Product<p>Applications An antiestrogen and antineoplastic. Nonsteroidal antiestrogen structurally similar to Tamoxifen. Toremifine has has been shown to reduce Ebola infection in rodents (3).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kallio, S., et al.: Cancer Chemother. Pharmacol., 17, 103 (1986), Valavaara, R., et al.: Eur. J. Cancer Clin. Oncol., 24, 785 (1988); (3) Chem. and Eng. News p9, July 4 (2016)<br></p>Formula:C26H28ClNO·C6H8O7Color and Shape:NeatMolecular weight:598.08Toremifene citrate
CAS:Controlled Product<p>Estrogen receptor modulator</p>Formula:C32H36ClNO8Purity:Min. 95%Color and Shape:PowderMolecular weight:598.08 g/mol
