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CAS 89797-00-2

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Iopentol

Description:
Iopentol is a non-ionic, water-soluble iodinated contrast agent primarily used in medical imaging, particularly in computed tomography (CT) scans and angiography. It is characterized by its low osmolality, which helps reduce the risk of adverse reactions compared to older contrast agents. Iopentol has a high iodine content, enhancing its radiopacity, allowing for clearer imaging of vascular structures and organs. The chemical structure of Iopentol includes multiple hydroxyl groups, contributing to its solubility and stability in aqueous solutions. It is generally well-tolerated, with a lower incidence of allergic reactions and nephrotoxicity compared to ionic contrast agents. Additionally, Iopentol is designed to be excreted rapidly by the kidneys, making it suitable for patients with varying renal function. Its safety profile and effectiveness make it a preferred choice in diagnostic radiology, although, like all contrast agents, it should be used with caution in patients with a history of contrast media reactions or renal impairment.
Formula:C20H28I3N3O9
InChI:InChI=1/C20H28I3N3O9/c1-9(29)26(5-12(32)8-35-2)18-16(22)13(19(33)24-3-10(30)6-27)15(21)14(17(18)23)20(34)25-4-11(31)7-28/h10-12,27-28,30-32H,3-8H2,1-2H3,(H,24,33)(H,25,34)
InChI key:InChIKey=IUNJANQVIJDFTQ-UHFFFAOYSA-N
SMILES:N(CC(COC)O)(C(C)=O)C1=C(I)C(C(NCC(CO)O)=O)=C(I)C(C(NCC(CO)O)=O)=C1I
Synonyms:
  • 1,3-Benzenedicarboxamide, 5-(acetyl(2-hydroxy-3-methoxypropyl)amino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-
  • 1,3-Benzenedicarboxamide, 5-[acetyl(2-hydroxy-3-methoxypropyl)amino]-N<sup>1</sup>,N<sup>3</sup>-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-
  • 5-[Acetyl(2-hydroxy-3-methoxypropyl)amino]-N<sup>1</sup>,N<sup>3</sup>-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
  • 5-[acetyl(2-hydroxy-3-methoxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
  • Imagopaque
  • Iopentol [USAN:INN:BAN]
  • Iopentolum
  • Iopentolum [Latin]
  • Ivepaque
  • N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2-hydroxy-3-methoxypropyl)acetamido)-2,4,6-triiodoisophthalamide
  • See more synonyms
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