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CAS 898168-15-5

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  • HI042
    Targetmol
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    HI042

    CAS:
    HI042 is an FMS-like tyrosine kinase 3 (FLT3) inhibitor, showing an IC50 value of 0.62 μM for MOLM-13 cells, 0.33 μM for MV4-11 cells, and 0.89 μM for OCI-AML3 cells. It selectively reduces the survival rate of FLT3-internal tandem duplication (FLT3-ITD) positive cell lines, induces apoptosis, disrupts cell cycle progression, and diminishes colony-forming ability. HI042 is applicable for acute myeloid leukemia (AML) research.
    Formula:C14H11N3O3S
    Color and Shape:Solid
    Molecular weight:301.32

    Ref: TM-T212451