CAS 89848-41-9

N-Desalkyl Itraconazole-d8

CAS: 89848-41-9

Formula: C₃₁H₂₂D₈Cl₂N₈O₄

Color and Shape: Off-White Solid

Molecular weight: 657.58

Ref: 4Z-I-0318

N-Desalkyl Itraconazole

CAS: 89848-41-9

Formula: C₃₁H₃₀Cl₂N₈O₄

Color and Shape: Off-White Solid

Molecular weight: 649.53

Ref: 4Z-I-0314

N-Desalkyl Itraconazole

Controlled Product

CAS: 89848-41-9

Applications N-Desalkyl Itraconazole is a derivative of itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.
References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),

Formula: C₃₁H₃₀Cl₂N₈O₄

Color and Shape: Neat

Molecular weight: 649.53

Ref: TR-D288345

N-Desalkyl Itraconazole-d8

Controlled Product

CAS: 89848-41-9

Formula: C₃₁D₈H₂₂Cl₂N₈O₄

Color and Shape: Neat

Molecular weight: 657.576

Ref: TR-D288347

N-Desalkyl itraconazole

CAS: 89848-41-9

N-Desalkyl itraconazole is a triazole antifungal drug that belongs to the group of medicines. It is used in the treatment of systemic mycoses, including blastomycosis and histoplasmosis. N-Desalkyl itraconazole has been shown to inhibit the growth of fungi by interfering with their cell membranes and inhibiting their production of ergosterol. Calibration studies have shown that this drug binds to human liver microsomes and plasma proteins, as well as transporters such as P-glycoprotein. These interactions may influence its pharmacokinetics, which can be determined using a bioanalytical method.

Formula: C₃₁H₃₀Cl₂N₈O₄

Purity: Min. 95%

Molecular weight: 649.53 g/mol

Ref: 3D-ID168102

N-Desalkyl Itraconazole

CAS: 89848-41-9

Formula: C₃₁H₃₀Cl₂N₈O₄

Molecular weight: 649.53

Ref: ST-EA-CP-I3010