2-Benzofurancarboxamide, N-[4-[4-(3-methylphenyl)-1-piperazinyl]butyl]- is a chemical compound characterized by its complex structure, which includes a benzofuran moiety and a piperazine ring. This compound typically exhibits properties associated with amides, such as moderate solubility in polar solvents and potential bioactivity due to its piperazine component, which is often linked to pharmacological effects. The presence of the 3-methylphenyl group suggests that it may interact with biological targets, potentially influencing its pharmacokinetics and pharmacodynamics. The compound's molecular structure may confer specific characteristics such as stability under certain conditions, and it may participate in hydrogen bonding due to the amide functional group. Additionally, the compound's synthesis and reactivity can be influenced by the substituents on the piperazine and benzofuran rings, which may affect its overall chemical behavior and applications in medicinal chemistry or material science. As with many organic compounds, safety and handling precautions are essential due to potential toxicity or reactivity.

2-BenzofurancarboxaMide, N-[4-[4-(3-Methylphenyl)-1-piperazinyl]butyl]-

898532-85-9: 2-Benzofurancarboxamide, N-[4-[4-(3-methylphenyl)-1-piperazinyl]butyl]- is a chemical compound characterized by its complex structure, which includes a benzofuran moiety and a piperazine ring. This compound typically exhibits properties associated with amides, such as moderate solubility in polar solvents and potential bioactivity due to its piperazine component, which is often linked to pharmacological effects. The presence of the 3-methylphenyl group suggests that it may interact with biological targets, potentially influencing its pharmacokinetics and pharmacodynamics. The compound's molecular structure may confer specific characteristics such as stability under certain conditions, and it may participate in hydrogen bonding due to the amide functional group. Additionally, the compound's synthesis and reactivity can be influenced by the substituents on the piperazine and benzofuran rings, which may affect its overall chemical behavior and applications in medicinal chemistry or material science. As with many organic compounds, safety and handling precautions are essential due to potential toxicity or reactivity.

D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.

CAS 898532-85-9

2-BenzofurancarboxaMide, N-[4-[4-(3-Methylphenyl)-1-piperazinyl]butyl]-

D3/5-HT receptor modulator-1

Ref: TM-T205297