CAS 898537-18-3

Luseogliflozin

Description:

Luseogliflozin is a medication primarily used in the management of type 2 diabetes mellitus. It belongs to the class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, which function by preventing the reabsorption of glucose in the kidneys, thereby promoting its excretion in urine and lowering blood glucose levels. The chemical structure of Luseogliflozin includes a specific arrangement of carbon, hydrogen, oxygen, and nitrogen atoms, contributing to its pharmacological activity. It is typically administered orally and is often used in conjunction with other antidiabetic agents to enhance glycemic control. Luseogliflozin has been shown to have additional benefits, such as weight loss and potential cardiovascular protection. As with any medication, it may have side effects, including urinary tract infections and dehydration, and its use should be monitored by healthcare professionals. Overall, Luseogliflozin represents a significant advancement in diabetes treatment, offering a novel mechanism of action to help manage blood sugar levels effectively.

Formula: C₂₃H₃₀O₆S

InChI: InChI=1S/C23H30O6S/c1-4-29-16-7-5-14(6-8-16)10-15-11-17(18(28-3)9-13(15)2)23-22(27)21(26)20(25)19(12-24)30-23/h5-9,11,19-27H,4,10,12H2,1-3H3/t19-,20-,21+,22-,23+/m1/s1

InChI key: InChIKey=WHSOLWOTCHFFBK-ZQGJOIPISA-N

SMILES: O(C)C1=C(C=C(CC2=CC=C(OCC)C=C2)C(C)=C1)[C@@H]3S[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O

Synonyms:

• TS 071
• (1S)-1,5-Dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-D-glucitol
• D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-, (1S)-
• Luseogliflozin
• (2S,3R,4R,5S,6R)-2-(5-(4-Ethoxybenzyl)-2-methoxy-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-thiopyran-3,4,5-triol
• Luseogliflozin,D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)-
• Luseogliflozin USP/EP/BP
• TS-71
• (Lusefi)
• (2S,3R,4R,5S,6R)-2-[5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl]-6-(hydroxymethyl)thiane-3,4,5-triol
• TS 071; TS071; TS-71

Luseogliflozin

CAS: 898537-18-3

Luseogliflozin inhibits SGLT2 for glucose uptake with 1.10 nM potency.

Formula: C₂₃H₃₀O₆S

Color and Shape: Solid

Molecular weight: 434.55

Ref: TM-T21399

Luseogliflozin

CAS: 898537-18-3

Formula: C₂₃H₃₀O₆S

Molecular weight: 434.55

Ref: 4Z-L-228001

Luseogliflozin

CAS: 898537-18-3

Luseogliflozin is a drug that belongs to the class of sodium glucose co-transporter 2 (SGLT2) inhibitors. It blocks the reabsorption of glucose in the kidney, thereby lowering blood glucose levels and improving glycemic control in patients with type 2 diabetes. Luseogliflozin is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are already treated with insulin or oral antidiabetic drugs. Luseogliflozin has been shown to have no effect on hepatic steatosis, but it does reduce blood pressure when administered with other antihypertensive agents. The long-term efficacy and safety of luseogliflozin has not yet been established. Luseogliflozin should be used with caution in patients who are also taking drugs that can inhibit or induce cytochrome P450 enzymes, such as ketoconazole, cimetidine, eryth

Formula: C₂₃H₃₀O₆S

Purity: Min. 95%

Molecular weight: 434.55 g/mol

Ref: 3D-BL168096

Luseogliflozin

Controlled Product

CAS: 898537-18-3

Applications Luseogliflozin is used n biological studies as a potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycemic activity.
References Yamamoto, K., et al.: Br. J. Pharmacol., 164, 181 (2011);

Formula: C₂₃H₃₀O₆S

Color and Shape: Neat

Molecular weight: 434.546

Ref: TR-L474950