CAS 89878-14-8

3-(Diethylboryl)pyridine

Description:

3-(Diethylboryl)pyridine is an organoboron compound characterized by the presence of a pyridine ring substituted with a diethylboryl group. This compound typically exhibits properties associated with both boron and nitrogen functionalities, making it a valuable intermediate in organic synthesis and materials science. The diethylboryl group contributes to its reactivity, particularly in cross-coupling reactions and as a potential ligand in coordination chemistry. The pyridine moiety provides basicity and can participate in hydrogen bonding, influencing the compound's solubility and interaction with other molecules. Additionally, 3-(Diethylboryl)pyridine may exhibit unique optical properties due to the presence of the boron atom, which can affect its electronic structure. Its applications may extend to catalysis, organic electronics, and the development of new materials. Safety considerations should be taken into account when handling this compound, as organoboron compounds can be sensitive to moisture and air, potentially leading to hydrolysis or oxidation.

Formula: C₉H₁₄BN

InChI: InChI=1/C9H14BN/c1-3-10(4-2)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3

InChI key: InChIKey=OJKBCQOJVMAHDX-UHFFFAOYSA-N

SMILES: B(CC)(CC)C=1C=CC=NC1

Synonyms:

• 3-(Diethylboranyl)Pyridine
• 3-(Diethylboryl)Pyridine
• 3-Diethylboropyridine
• 3-Pyridinyldiethylborane
• 3-Pyridyldiethyl borane
• 3-Pyridyldiethylborane
• Abiraterone interMediate
• Debp
• Diethyl(3-(4-Pyridin-3-yl) borane
• Diethyl(3-Pyridinyl)-Borane
• Diethyl-(pyridin-3-yl)-borane
• Diethyl-3-pyridylborane
• Dithyl(3-pyridyl)Borane
• Pyridine, 3-(diethylboryl)-

Diethyl(3-pyridyl)borane

CAS: 89878-14-8

Formula: C₉H₁₄BN

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 147.03

Ref: 3B-D2661

Diethyl(3-pyridyl)borane, 98%

CAS: 89878-14-8

Reactant for: preparation of inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents, N-Methylation reactions of the pyridyl group, Palladium catalyzed amination reactions, intramolecular Heck reactions, Coupling reactions and Synthesis of tri

Formula: C₉H₁₄BN

Purity: 98%

Molecular weight: 147.03

Ref: 02-H64225

Diethyl(3-pyridyl)borane

CAS: 89878-14-8

Formula: C₉H₁₄BN

Purity: 97%

Color and Shape: Solid

Molecular weight: 147.0252

Ref: IN-DA0036ZI

Diethyl-(3-pyridyl)borane

CAS: 89878-14-8

Diethyl-(3-pyridyl)borane

Formula: C₉H₁₄BN

Purity: 98%

Color and Shape: white solid

Molecular weight: 147.03g/mol

Ref: 54-OR315000

Diethyl(3-pyridinyl)borane

CAS: 89878-14-8

Color and Shape: Neat

Ref: 86-MM3504.02

Abiraterone Impurity 7

CAS: 89878-14-8

Formula: C₉H₁₄BN

Molecular weight: 147.03

Ref: 4Z-A-8240

Diethyl(3-pyridinyl)borane

CAS: 89878-14-8

Formula: C₉H₁₄BN

Purity: 95%

Color and Shape: Solid

Molecular weight: 147.03

Ref: 10-F208990

3-(Diethylboryl)pyridine

Controlled Product

CAS: 89878-14-8

Impurity Abiraterone Impurity 7
Applications 3-(Diethylboryl)pyridine is an intermediate used to prepare inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents. It is also used in the synthesis of trisubstituted pyrimidines from polyhalopyrimidines via Suzuki coupling.
References Charrier, J., et al.; J. Med. Pharm. Chem., 54, 2320 (2011); Large, J., et al.: Synlett., 861 (2006)

Formula: C₉H₁₄BN

Color and Shape: Neat

Molecular weight: 147.02

Ref: TR-D442040

Diethyl(3-pyridyl)borane

CAS: 89878-14-8

Formula: C₉H₁₄BN

Molecular weight: 147.03

Ref: ST-EA-CP-A67041

3-(Diethylboryl) pyridine

CAS: 89878-14-8

3-(Diethylboryl) pyridine is a halogenated biphenyl. It is used in the synthesis of 3-aryl substituted pyridines by cross-coupling reactions with aryl iodides, bromides and chlorides. Cross-coupling reactions are usually carried out at low temperatures (0 to 20°C) in order to minimize side reactions. The reaction is usually conducted in a biphasic system containing an organic solvent and water, which facilitates the extraction of the product from the mixture. 3-(Diethylboryl) pyridine reacts with halide ions via an electrophilic substitution reaction to form a reactive intermediate, which reacts with palladium catalyst to produce the desired product. This process is also called catalytic hydrogenation. 3-(Diethylboryl) pyridine has been shown to inhibit human cytochrome P450 enzymes, which are involved in drug metabolism and break down drugs

Formula: C₉H₁₄BN

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 147.03 g/mol

Ref: 3D-FD29987