Transforming Growth Factor Alpha (TGF-α) is a polypeptide growth factor that plays a crucial role in cell proliferation, differentiation, and development. It is primarily involved in the regulation of epithelial cell growth and has significant implications in various physiological and pathological processes, including wound healing and tumorigenesis. TGF-α is produced by a variety of cell types and exerts its effects by binding to the epidermal growth factor receptor (EGFR), triggering a cascade of intracellular signaling pathways that promote cell division and survival. The substance with the CAS number 89899-53-6 specifically refers to the rat form of TGF-α, which shares structural and functional similarities with its human counterpart. This growth factor is often studied in the context of cancer research, as its overexpression is associated with several malignancies. Additionally, TGF-α is involved in the regulation of immune responses and has been implicated in the pathogenesis of various diseases, making it a significant target for therapeutic interventions.

transforming growth factor-A rat

89899-53-6: Transforming Growth Factor Alpha (TGF-α) is a polypeptide growth factor that plays a crucial role in cell proliferation, differentiation, and development. It is primarily involved in the regulation of epithelial cell growth and has significant implications in various physiological and pathological processes, including wound healing and tumorigenesis. TGF-α is produced by a variety of cell types and exerts its effects by binding to the epidermal growth factor receptor (EGFR), triggering a cascade of intracellular signaling pathways that promote cell division and survival. The substance with the CAS number 89899-53-6 specifically refers to the rat form of TGF-α, which shares structural and functional similarities with its human counterpart. This growth factor is often studied in the context of cancer research, as its overexpression is associated with several malignancies. Additionally, TGF-α is involved in the regulation of immune responses and has been implicated in the pathogenesis of various diseases, making it a significant target for therapeutic interventions.

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CAS 89899-53-6

transforming growth factor-A rat

TGF α (1-50) (rat) trifluoroacetate salt

Ref: 3D-FT109537

TGF α (1-50) (rat)

Ref: 01-4031309