CAS 89943-82-8

Cicletanine

Description:

Cicletanine is a chemical compound classified as a diuretic and antihypertensive agent, primarily used in the treatment of hypertension. It is known for its ability to promote the excretion of sodium and water from the body, thereby reducing blood volume and lowering blood pressure. Cicletanine functions by inhibiting the reabsorption of sodium in the renal tubules, which enhances diuresis. The compound has a unique structure that contributes to its pharmacological effects, and it is often administered in oral form. In addition to its diuretic properties, cicletanine may also exhibit vasodilatory effects, which can further aid in managing high blood pressure. Its safety profile and side effects are generally well-documented, making it a viable option for patients with specific cardiovascular conditions. As with any medication, it is essential for patients to consult healthcare professionals for appropriate usage and potential interactions with other drugs.

Formula: C₁₄H₁₂ClNO₂

InChI: InChI=1S/C14H12ClNO2/c1-8-13(17)12-7-18-14(11(12)6-16-8)9-2-4-10(15)5-3-9/h2-6,14,17H,7H2,1H3

InChI key: InChIKey=CVKNDPRBJVBDSS-UHFFFAOYSA-N

SMILES: OC1=C2C(C(OC2)C3=CC=C(Cl)C=C3)=CN=C1C

Synonyms:

• (+-)-3-(p-Chlorophenyl)-1,3-dihydro-6-methylfuro(3,4-c)pyridin-7-ol
• (+-)-Bn-1270
• 3-(4-Chlorophenyl)-1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol
• 3-(4-Chlorophenyl)-6-Methyl-1,3-Dihydrofuro[3,4-C]Pyridin-7-Ol
• Cicletanide
• Cicletanina
• Cicletanina [Spanish]
• Cicletanine [USAN:INN:BAN]
• Cicletaninum
• Cicletaninum [Latin]
• Cycletanide
• Furo(3,4-c)pyridin-7-ol, 3-(4-chlorophenyl)-1,3-dihydro-6-methyl-, (+-)-
• Unii-Chg7Qc509W
• Win 90,000

Cicletanine

CAS: 89943-82-8

Cicletanine is a novel synthetic peptide that is a selective activator of the TRPM7 ion channel. It blocks the intracellular calcium release channels, which are responsible for the secretion of neurotransmitters and hormones. Cicletanine also inhibits L-type voltage-gated calcium channels, leading to reduced production of nitric oxide. This drug has been shown to be effective in animal models of pain and inflammation.

Formula: C₁₄H₁₂ClNO₂

Purity: Min. 95%

Molecular weight: 261.7 g/mol

Ref: 3D-PDA94382