CAS 90-33-5

4-Methylumbelliferone

Description:

4-Methylumbelliferone, also known as 7-methyl-2H-chromen-2-one, is a chemical compound with the CAS number 90-33-5. It belongs to the class of coumarins, which are aromatic compounds characterized by a benzopyrone structure. This substance is typically a yellow crystalline solid that is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but has limited solubility in water. 4-Methylumbelliferone exhibits fluorescence properties, making it useful as a fluorescent probe in biochemical assays. It is known for its role as a substrate for certain enzymes, particularly in the study of glucuronidation processes. Additionally, this compound has been investigated for its potential therapeutic effects, including anti-inflammatory and anti-cancer properties. Its ability to inhibit certain enzymes, such as hyaluronidase, has garnered interest in the fields of pharmacology and biochemistry. Overall, 4-Methylumbelliferone is a versatile compound with applications in research and potential medicinal uses.

Formula: C₁₀H₈O₃

InChI: InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3

InChI key: InChIKey=HSHNITRMYYLLCV-UHFFFAOYSA-N

SMILES: CC=1C=2C(OC(=O)C1)=CC(O)=CC2

Synonyms:

• 4-Methyl-7-hydroxycoumarin
• 4-Methylumbelliferone
• 4-Mu
• 7-Hydroxy-4-methycoumarin
• 7-Hydroxy-4-methyl-2-chromenone
• 7-Hydroxy-4-methyl-2-oxo-3-chromene
• 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one
• 7-Hydroxy-4-methyl-2H-chomen-2-one
• 7-Hydroxy-4-methyl-2H-chromen-2-on
• 7-Hydroxy-4-methyl-2H-chromen-2-one
• 7-Hydroxy-4-methylbenzopyran-2-one
• 7-Hydroxy-4-methylcoumarin
• 7-Hydroxyl-4-methylcoumarine
• Benzopyran(2H-1)-2-One, 7-Hydroxy-4-Methyl-
• Bilcolic
• Bilicante
• Biliton H
• Cantabilin
• Cantabiline
• Cholestil
• Cholonerton
• Cholspasmin
• Coumarin 4
• Coumarin 456
• Coumarin, 7-hydroxy-4-methyl-
• Cumarote C
• Eurogale
• Himecol
• Himecromona
• Hymecromon
• Hymecromone
• Imecromone
• Lm 94
• Medilla
• Mendiaxon
• Nsc 19026
• Nsc 9408
• Odeston
• Omega 127
• Pilot 447
• Umbelliferone, 4-methyl-
• β-Methylumbelliferone
• imechromone
• 2H-1-Benzopyran, 7-hydroxy-4-methyl-2-oxo-
• 7-hydroxy-4-methylbenzpyrone
• 7-hydroxy-4-methyl-2,h-1-benzo-pyran-2-one
• beta-methylumbelliferone
• eurogae
• 2H-1-Benzopyran-2-one, 7-hydroxy-4-methyl-

4-Methylumbelliferone

CAS: 90-33-5

Formula: C₁₀H₈O₃

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 176.17

Ref: 3B-M0453

4-Methylumbelliferone, 97%

CAS: 90-33-5

4-Methylumbelliferone is used in the determination of nitric acid and as a standard for fluorometric determination of enzyme activity. It is also used in bile therapy. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label

Formula: C₁₀H₈O₃

Purity: 97%

Color and Shape: White to cream to pale yellow to pale brown, Crystals or powder or crystalline powder

Molecular weight: 176.17

Ref: 02-A10337

HYMECROMONE CRS

CAS: 90-33-5

HYMECROMONE CRS

Formula: C₁₀H₈O₃

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 176.1687

Ref: 41-Y0000011

4-Methylumbelliferone

CAS: 90-33-5

4-Methylumbelliferone: coumarin derivative, used as spasmolytic, choleretic, light-protective agent, and to detect nitric acid.

Formula: C₁₀H₈O₃

Purity: 97.32% - 97.70%

Color and Shape: Less Crystals Insoluble In Water (Ntp 1992) Physical Description Colorless Crystals Insoluble In Water (Ntp 1992)

Molecular weight: 176.17

Ref: TM-T1391

7-Hydroxy-4-methyl-2H-chromen-2-one

CAS: 90-33-5

Formula: C₁₀H₈O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 176.1687

Ref: IN-DA006RML

Hymecromone

CAS: 90-33-5

Formula: C₁₀H₈O₃

Molecular weight: 176.17

Ref: 4Z-H-092001

4-Methylumbelliferone

CAS: 90-33-5

4-Methylumbelliferone

Purity: ≥95%

Molecular weight: 176.17g/mol

Ref: 54-BUP14674

4-Methylumbelliferone

CAS: 90-33-5

Formula: C₁₀H₈O₃

Purity: 98.0 - 102.0 % (anhydrous basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 176.17

Ref: 7W-GE8143

7-Hydroxy-4-methylcoumarin

CAS: 90-33-5

7-Hydroxy-4-methylcoumarin

Formula: C₁₀H₈O₃

Purity: ≥95%

Color and Shape: white solid

Molecular weight: 176.17g/mol

Ref: 54-OR7969

4-Methylumbelliferone

CAS: 90-33-5

Formula: C₁₀H₈O₃

Purity: 95%~99%

Molecular weight: 176.171

Ref: BP-SBP03388

Hymecromone

Controlled Product

CAS: 90-33-5

Formula: C₁₀H₈O₃

Color and Shape: Neat

Molecular weight: 176.17

Ref: 86-MM0294.00

4-Methylumbelliferone

CAS: 90-33-5

Formula: C₁₀H₈O₃

Color and Shape: Neat

Molecular weight: 176.17

Ref: 04-C15146000

4-Methylumbelliferone

Controlled Product

CAS: 90-33-5

Formula: C₁₀H₈O₃

Color and Shape: White To Light Yellow

Molecular weight: 176.17

Ref: TR-M333000

4-Methylumbelliferone

CAS: 90-33-5

4-Methylumbelliferone is a coumarin derivative that inhibits the activity of enzymes such as p-nitrophenyl phosphate oxidase and aminopeptidase. It is used in vitro to study oxidative injury, which plays a role in the pathogenesis of inflammatory diseases, including primary sclerosing cholangitis and bone marrow transplantation. 4-Methylumbelliferone has been shown to induce apoptosis by increasing reactive oxygen species levels and activating toll-like receptor 4 (TLR4). It also has inhibitory effects on osteosarcoma cell proliferation in vitro.

Formula: C₁₀H₈O₃

Molecular weight: 176.17 g/mol

Ref: 3D-M-5421

4-Methylumbelliferone

CAS: 90-33-5

4-Methylumbelliferone is a coumarin derivative compound used as chemopreventive and therapeutic agent for prostate cancer. It is a fluorogenic substrate use for the detection of E.coli and other bacteria.

Formula: C₁₀H₈O₃

Color and Shape: Off-White Powder

Molecular weight: 176.17 g/mol

Ref: 3D-FM00596

4-Methylumbelliferone

CAS: 90-33-5

Standard for fluorometric determination of enzyme activity. Hyaluronan synthesis inhibitor.

Formula: C₁₀H₈O₃

Purity: Min. 97.5 Area-%

Molecular weight: 176.17 g/mol

Ref: 3D-M-5410

ß-Methylumbelliferone extrapure AR, 98%

CAS: 90-33-5

Formula: C₁₀H₈O₃

Purity: min. 98% By Titration

Color and Shape: White to light yellow, Crystalline compound or powder

Molecular weight: 176.17

Ref: SR-18040

7-Hydroxy-4-methyl-2H-chromen-2-one

CAS: 90-33-5

Formula: C₁₀H₈O₃

Purity: 95%

Color and Shape: Beige powder

Molecular weight: 176.171

Ref: 10-F093391

Hymecromone

CAS: 90-33-5

Color and Shape: Neat

Ref: 61-FOR0294.00