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CAS 90-89-1

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Diethylcarbamazine

Description:
Diethylcarbamazine (DEC) is an anthelmintic medication primarily used to treat filarial infections, such as lymphatic filariasis and onchocerciasis. It is a synthetic compound characterized by its chemical structure, which includes a carbamate functional group. DEC is typically presented as a white to off-white crystalline powder that is soluble in organic solvents like ethanol and chloroform but has limited solubility in water. The substance acts by immobilizing and killing the microfilariae, which are the larval forms of filarial worms, thereby aiding in their elimination from the host. DEC is known for its relatively low toxicity, although it can cause mild side effects such as fever, headache, and gastrointestinal disturbances. The compound is administered orally and is often used in mass drug administration programs in endemic regions. Its effectiveness and safety profile make it a valuable tool in public health efforts to control and eliminate filarial diseases.
Formula:C10H21N3O
InChI:InChI=1S/C10H21N3O/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13/h4-9H2,1-3H3
InChI key:InChIKey=RCKMWOKWVGPNJF-UHFFFAOYSA-N
SMILES:C(N(CC)CC)(=O)N1CCN(C)CC1
Synonyms:
  • 1-(N,N-Diethylcarbamoyl)-4-methylpiperazine
  • 1-Diethylcarbamoyl-4-methylpiperazine
  • 1-Methyl-4-diethylcarbamoylpiperazine
  • 1-Methyl-4-diethylcarbamylpiperazine
  • 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-
  • 84L
  • Bitirazine
  • Caracide
  • Carbamazine
  • Carbilazine
  • See more synonyms
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