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CAS 9000-86-6

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Alanine aminotransferase

Description:
Alanine aminotransferase (ALT), also known as serum glutamate-pyruvate transaminase (SGPT), is an enzyme primarily found in the liver, playing a crucial role in amino acid metabolism. It catalyzes the reversible transfer of an amino group from alanine to alpha-ketoglutarate, producing pyruvate and glutamate. This reaction is vital for gluconeogenesis and the urea cycle. ALT is a key biomarker for liver health; elevated levels in the bloodstream can indicate liver damage or disease, such as hepatitis or cirrhosis. The enzyme is a protein composed of amino acids and is typically measured in units per liter in clinical settings. Its activity can be influenced by various factors, including age, sex, and the presence of liver disease. In laboratory diagnostics, ALT is often assessed alongside aspartate aminotransferase (AST) to provide a more comprehensive view of liver function. Understanding ALT levels is essential for diagnosing and monitoring liver conditions, making it a significant focus in clinical biochemistry.
Formula:C11H16N2O6
Synonyms:
  • <span class="text-smallcaps">L</span>-Alanine aminotransferase
  • <span class="text-smallcaps">L</span>-Alanine transaminase
  • <span class="text-smallcaps">L</span>-Alanine-α-ketoglutarate aminotransferase
  • ALT
  • Alanine aminotransferase
  • Alanine aminotransferases
  • Alanine oxaloacetate aminotransferases
  • Alanine oxoglutarate aminotransferase
  • Alanine pyruvate aminotransferases
  • Alanine transaminase
  • See more synonyms
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Found 3 products.
  • Glutamic-pyruvate Transaminase

    CAS:
    Color and Shape:Light-yellow to yellow-green lyophilised powder

    Ref: 7W-GZ1654

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  • Alanine aminotransferase

    CAS:
    Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-
    Purity:98%
    Color and Shape:Solid
  • Glutamic pyruvic transaminase

    CAS:
    <p>Glutamic pyruvic transaminase (also Alanine transaminase, alanine aminotransferase; E.C. 2.6.1.2) is an enzyme that catalyzes the following reaction:  L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate  One unit of Glutamic pyruvic transaminase will catalyze the conversion of 1.0 µmole per minute of L-alanine and α-ketoglutarate to L-glutamate and pyruvate, at 37°C and pH 7.4.</p>
    Color and Shape:Powder
    Molecular weight:272.25 g/mol

    Ref: 3D-JAA00086

    1KU
    320.00€
    5KU
    886.00€
    10KU
    1,193.00€