D-Amino acid oxidase (DAAO) is an enzyme that catalyzes the oxidative deamination of D-amino acids, converting them into their corresponding α-keto acids while producing ammonia and hydrogen peroxide as byproducts. This enzyme is primarily found in the brain and plays a crucial role in the metabolism of D-amino acids, which are less common than their L-counterparts but are important in various biological processes, including neurotransmission and the regulation of certain physiological functions. DAAO is a flavoprotein, meaning it contains a flavin cofactor, which is essential for its enzymatic activity. The enzyme exhibits specificity for D-amino acids, such as D-serine, which is significant in the context of neurobiology, particularly in relation to glutamate signaling and potential implications in psychiatric disorders. DAAO's activity can be influenced by various factors, including pH, temperature, and the presence of inhibitors or activators. Its study is important for understanding metabolic pathways and developing therapeutic strategies for conditions linked to D-amino acid dysregulation.

D-Amino acid oxidase

9000-88-8: D-Amino acid oxidase (DAAO) is an enzyme that catalyzes the oxidative deamination of D-amino acids, converting them into their corresponding α-keto acids while producing ammonia and hydrogen peroxide as byproducts. This enzyme is primarily found in the brain and plays a crucial role in the metabolism of D-amino acids, which are less common than their L-counterparts but are important in various biological processes, including neurotransmission and the regulation of certain physiological functions. DAAO is a flavoprotein, meaning it contains a flavin cofactor, which is essential for its enzymatic activity. The enzyme exhibits specificity for D-amino acids, such as D-serine, which is significant in the context of neurobiology, particularly in relation to glutamate signaling and potential implications in psychiatric disorders. DAAO's activity can be influenced by various factors, including pH, temperature, and the presence of inhibitors or activators. Its study is important for understanding metabolic pathways and developing therapeutic strategies for conditions linked to D-amino acid dysregulation.

D-Amino acid oxidase enzyme metabolizes and detoxifies exogenous D-amino acids, regulating D-serine in the brain.

CAS 9000-88-8

D-Amino acid oxidase

D-Amino acid oxidase

Ref: TM-T76170

D-Amino Acid Oxidase (DAA, DAO, DAMOX) ex. Porcine Kidney, 6000U/g powder

Ref: SR-68384