Kallikrein is a serine protease enzyme that plays a crucial role in various physiological processes, including blood pressure regulation, inflammation, and pain perception. It is part of the kallikrein-kinin system, which is involved in the generation of kinins, potent vasodilators that influence vascular permeability and smooth muscle contraction. Kallikrein is produced primarily in the pancreas and kidneys and is secreted as an inactive precursor, which is activated in response to specific physiological stimuli. The enzyme exhibits substrate specificity for peptide bonds adjacent to lysine or arginine residues, facilitating the cleavage of proteins and peptides. Kallikrein is also implicated in various pathological conditions, including cardiovascular diseases and certain cancers, making it a target for therapeutic interventions. Its activity can be influenced by various factors, including pH, temperature, and the presence of inhibitors. Overall, kallikrein is a vital enzyme with significant implications in both health and disease, reflecting its importance in biochemical and clinical research.

Kallikrein

9001-01-8: Kallikrein is a serine protease enzyme that plays a crucial role in various physiological processes, including blood pressure regulation, inflammation, and pain perception. It is part of the kallikrein-kinin system, which is involved in the generation of kinins, potent vasodilators that influence vascular permeability and smooth muscle contraction. Kallikrein is produced primarily in the pancreas and kidneys and is secreted as an inactive precursor, which is activated in response to specific physiological stimuli. The enzyme exhibits substrate specificity for peptide bonds adjacent to lysine or arginine residues, facilitating the cleavage of proteins and peptides. Kallikrein is also implicated in various pathological conditions, including cardiovascular diseases and certain cancers, making it a target for therapeutic interventions. Its activity can be influenced by various factors, including pH, temperature, and the presence of inhibitors. Overall, kallikrein is a vital enzyme with significant implications in both health and disease, reflecting its importance in biochemical and clinical research.

<p>Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .</p>

CAS 9001-01-8

Kallikrein

Kallikrein

Ref: TM-T73611

Kallidinogenase RS

Ref: 2K-1038000021