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CAS 9001-12-1

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Collagenase

Description:
Collagenase, with the CAS number 9001-12-1, is an enzyme that specifically catalyzes the breakdown of collagen, a key structural protein found in connective tissues. This enzyme is produced by various organisms, including bacteria and certain types of fungi, and is crucial in biological processes such as tissue remodeling and wound healing. Collagenase exhibits proteolytic activity, meaning it cleaves peptide bonds in proteins, particularly those in collagen, leading to the degradation of the extracellular matrix. It is commonly used in laboratory settings for cell culture applications, where it aids in the dissociation of tissues into single-cell suspensions. Additionally, collagenase has therapeutic applications in medicine, particularly in the treatment of conditions like Dupuytren's contracture and chronic wounds, where it helps to break down excessive collagen deposits. The enzyme is typically characterized by its specificity for collagen substrates, optimal activity at physiological pH, and temperature ranges, making it a valuable tool in both research and clinical settings.
Formula:Unspecified
Synonyms:
  • Aspergillopeptidase C
  • Azocollase
  • Brachyurin
  • COLLAGENASE 125 u / mg
  • Clostridiopeptidase I
  • Clostridiopeptidase II
  • Clostridium histolyticum collagenase
  • Colagenasa
  • Collagen peptidase
  • Collagen protease
  • See more synonyms
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