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CAS 9001-18-7

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Lipoamide dehydrogenase

Description:
Lipoamide dehydrogenase, with the CAS number 9001-18-7, is an enzyme that plays a crucial role in cellular metabolism, particularly in the oxidative decarboxylation of alpha-keto acids. This enzyme is part of the larger family of flavoproteins and is primarily involved in the regeneration of lipoic acid, which is essential for various enzymatic reactions. Lipoamide dehydrogenase catalyzes the reduction of lipoamide to dihydrolipoamide, utilizing NADH as a reducing agent. It is typically found in the mitochondria of eukaryotic cells and is important for energy production and the metabolism of carbohydrates, fats, and proteins. The enzyme exhibits a high degree of specificity for its substrates and is sensitive to changes in pH and temperature, which can affect its activity. Additionally, lipoamide dehydrogenase is involved in redox reactions, contributing to the cellular antioxidant defense system. Its activity can be influenced by various factors, including the presence of cofactors and inhibitors, making it a subject of interest in biochemical research and potential therapeutic applications.
Formula:Unspecified
Synonyms:
  • Dehydrogenase, Lipoamid-
  • Deshidrogenasa, Lipoamida
  • Deshydrogenase, Lipoamide
  • Diaphorase
  • Dihydrolipoamide dehydrogenase
  • Dihydrolipoate dehydrogenase
  • Dihydrolipoic dehydrogenase
  • Dihydrolipoyl dehydrogenase
  • Dihydrothioctic dehydrogenase
  • E.C. 1.6.4.3
  • See more synonyms
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