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CAS 9001-45-0

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Beta-glucuronidase

Description:
Beta-glucuronidase is an enzyme that catalyzes the hydrolysis of glucuronides, which are compounds formed by the conjugation of glucuronic acid to various substrates, including drugs and endogenous compounds. This enzyme plays a crucial role in the metabolism and excretion of various substances in the body, particularly in the liver and kidneys. Beta-glucuronidase is produced by various organisms, including bacteria and mammals, and is involved in the detoxification processes. It is characterized by its specificity for beta-D-glucuronides and is often studied in the context of pharmacology and toxicology due to its role in drug metabolism. The enzyme is also of interest in clinical diagnostics, as elevated levels can indicate certain pathological conditions. In laboratory settings, beta-glucuronidase is utilized in various assays and research applications, including studies on drug interactions and the biotransformation of xenobiotics. Its activity can be influenced by factors such as pH, temperature, and the presence of inhibitors or activators.
Formula:Unspecified
Synonyms:
  • 4-O-Methylglucuronidase
  • Acid β-<span class="text-smallcaps">D</span>-glucuronidase
  • Acid β-D-glucuronidase
  • Beta-Glucuronidase
  • E.C. 3.2.1.31
  • Ec 3.2.1.31
  • Exo-β-<span class="text-smallcaps">D</span>-glucuronidase
  • Exo-β-D-glucuronidase
  • GUS
  • Glucuronidasa, Β-
  • See more synonyms
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100
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50
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90
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95
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100
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