CAS 9001-48-3

Glutathione reductase

Description:

Glutathione reductase is an essential enzyme that plays a critical role in cellular antioxidant defense by catalyzing the reduction of oxidized glutathione (GSSG) to its reduced form (GSH) using NADPH as a cofactor. This enzyme is crucial for maintaining the balance of glutathione, a tripeptide composed of glutamine, cysteine, and glycine, which protects cells from oxidative stress and maintains redox homeostasis. Glutathione reductase is found in various organisms, including bacteria, plants, and animals, and is predominantly located in the cytoplasm and mitochondria. The enzyme operates optimally at physiological pH and temperature, and its activity can be influenced by various factors, including the presence of metal ions and other cofactors. Dysregulation of glutathione reductase activity has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting its importance in health and disease. Its CAS number, 9001-48-3, is used for identification in chemical databases and regulatory contexts.

Formula: NULL

Synonyms:

• E.C. 1.6.4.2
• E.C. 1.8.1.7
• Ec 1.6.4.2
• Ec 1.8.1.7
• GSH reductase
• GSH reductases
• GSSG reductase
• GSSG reductases
• Glutathione Reductase bakers yeast (S. cerevisiae)
• Glutathione S-reductase
• Glutathione disulfide oxidoreductase
• Glutathione disulfide oxidoreductases
• Glutathione disulfide reductase
• Glutathione disulfide reductases
• Glutathione reductase
• Glutathione reductases
• NADP-dependent glutathione reductase
• NADPH-GSSG reductase
• NADPH-glutathione reductase
• Reductasa, Glutation
• Reductase, Glutathion
• Reductase, glutathione
• Reduktase, Glutathion-
• GLUTATHIONE REDUCTASE FROM BAKER'S &
• Glutathione Reductase, from Yeast[GR]
• glutathione reductase from baker's yeast (s. cerevisiae)
• Glutathione Reductase from Human, Recombinant
• GR/Glutathione Reductase froM baker's yeast
• NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE II
• GLUTATHIONE REDUCTASE TYPE VI
• glutathione reductase from spinach
• Glutathione Reductase from bovine intestinal mucosa
• glutathione reductase from baker'S yeast
• GLUTATHIONE REDUCTASE, YEAST
• Glutathione Reductase human
• GLUTATHIONE REDUCTASE FROM BAKER'S YEAST , ~100 U/MG
• GLUTATHIONE REDUCTASE TYPE VI FROM*SPINA CH
• NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE VI
• GR TYPE VI
• GlutathioneReductaseExYeast(E.C.1.6.4.2)
• Glutathionereductaseexyeast
• GLUTATHIONE REDUCTASE TYPE II
• Native Bakers yeast (S. cerevisiae) Glutathione Reductase
• GLUTATHIONE REDUCTASE TYPE II CRUDE*FROM WHEAT GERM
• Glutathione Reductase from baker's yeast (S. cerevisiae),GR, NAD(P)H:oxidized-glutathione oxidoreductase
• Glutathionereductase, 189units/mg protein
• GR, (NAD(P)H): oxidized-glutathione oxidoreductase
• Glutathione Reductase from spinach,GR, NAD(P)H: oxidized-glutathione oxidoreductase
• NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE
• glutathione reductase from wheat germ
• Glutathione reductase from E. coli, Recombinant
• GR
• GR TYPE II
• Glutathione reductase (NAD(P)H) from Yeast, 50% glycerol solution
• Native Wheat germ Glutathione Reductase

Glutathione reductase

CAS: 9001-48-3

Glutathione reductase (EC 1.6.4.2) is an enzyme that ensures the availability of reduced glutathione [1].

Color and Shape: Solid

Ref: TM-T78342

Glutathione Reductase, baker's yeast

CAS: 9001-48-3

Glutathione Reductase, baker's yeast, is an enzyme derived from the yeast species *Saccharomyces cerevisiae*. This enzyme is sourced from baker's yeast, providing a renewable and consistent product for various biochemical applications. Its mode of action involves catalyzing the reduction of glutathione disulfide (GSSG) to the sulfhydryl form glutathione (GSH), using NADPH as an electron donor. This reaction is crucial for maintaining the intracellular redox balance by regenerating GSH, the primary cellular antioxidant.

Ref: 3D-EG184393