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CAS 9001-50-7

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Glyceraldehyde phosphate dehydrogenase

Description:
Glyceraldehyde phosphate dehydrogenase (GAPDH) is an enzyme that plays a crucial role in the glycolytic pathway, facilitating the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate while reducing NAD+ to NADH. This enzyme is a key player in cellular metabolism, particularly in energy production and the regulation of various metabolic processes. GAPDH is typically found in the cytoplasm of cells and is highly conserved across different species, indicating its essential function in cellular respiration. The enzyme operates optimally under specific pH and temperature conditions, which can vary depending on the organism. In addition to its metabolic role, GAPDH has been implicated in various cellular functions, including apoptosis and gene regulation, and has been studied for its potential involvement in diseases such as cancer and neurodegenerative disorders. Its structure typically consists of multiple subunits, contributing to its stability and functionality. Overall, GAPDH is a vital enzyme with diverse roles in both metabolism and cellular regulation.
Formula:C3H7O6P
Synonyms:
  • E.c. 1.2.1.12
  • Glyceraldehyde 3-phosphate dehydrogenase
  • E.C. 1.2.1.12
  • Glyceraldehyde phosphate dehydrogenase
  • Dehydrogenase, glyceraldehyde phosphate
  • Phosphoglyceraldehyde dehydrogenase
  • glyceraldehyde-3-phoshate dehydrogenase(rabbit muscle)
  • GAPDH
  • D-GLYCERALDEHYDE 3-PHOSPHATE: NAD+ OXIDOREDUCTASE [PHOSPHORYLATING]
  • gapd
  • See more synonyms
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Found 2 products.
  • CymitQuimica logo
    Targetmol
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    Glyceraldehyde phosphate dehydrogenase

    CAS:
    <p>Glyceraldehyde phosphate dehydrogenase, targeted by anti-thymocyte and anti-apoptotic agents, catalyzes the oxidation of reduced nicotinamide adenine</p>
    Color and Shape:Solid

    Ref: TM-T78360

  • Glyceraldehyde-3-phosphate dehydrogenase
    Biosynth
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    Glyceraldehyde-3-phosphate dehydrogenase

    CAS:
    <p>75u/mg - Glyceraldehyde 3-phosphate dehydrogenase (GAPDH; EC 1.2.1.12) is an enzyme that catalyzes the following reaction:  glyceraldehyde 3-phosphate + NAD+ + Pi ⇌ glycerate 1,3-bisphosphate + NADH + H+  One unit of GAPDH will convert 1.0 μmole of glyceraldehyde 3-phosphate into glycerate 1,3-bisphosphate per minute at pH 8.5 and 37 °C in the presence of NAD+ and phosphate. NAD+ is available here.</p>
    Formula:C3H7O6P
    Purity:Min. 95%
    Molecular weight:170.06 g/mol

    Ref: 3D-JAA00150

    500U
    443.00€