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CAS 9001-59-6

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Pyruvate kinase

Description:
Pyruvate kinase is an enzyme that plays a crucial role in the glycolytic pathway, catalyzing the conversion of phosphoenolpyruvate (PEP) to pyruvate while generating ATP from ADP. It is a key regulatory enzyme in cellular metabolism, particularly in the energy production process. Pyruvate kinase exists in several isoforms, which are found in different tissues and have distinct regulatory properties. The enzyme is activated by fructose-1,6-bisphosphate and inhibited by ATP and alanine, reflecting the energy status of the cell. Pyruvate kinase is a tetrameric protein, and its activity can be influenced by various factors, including allosteric effectors and covalent modifications. The enzyme is essential for maintaining the balance of glycolysis and gluconeogenesis, and its dysfunction can lead to metabolic disorders, including certain types of hemolytic anemia. The CAS number 9001-59-6 identifies pyruvate kinase in chemical databases, facilitating its study and application in biochemical research and clinical diagnostics.
Formula:NULL
Synonyms:
  • E.C. 2.7.1.40
  • Ec 2.7.1.40
  • Fluorokinase
  • Fluorokinases
  • Kinase (Phosphorylante), Pyruvate
  • Kinase (phosphorylating), fluoro-
  • Kinase (phosphorylierend), Pyruvat
  • Phosphoenolpyruvate kinase
  • Protein kinase Pyk
  • Pyruvate kinase
  • See more synonyms
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