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CAS 9001-80-3

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Phosphofructokinase

Description:
Phosphofructokinase (PFK) is a crucial enzyme in the glycolytic pathway, primarily responsible for catalyzing the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key regulatory step in glucose metabolism. It is a highly regulated enzyme, influenced by various metabolites such as ATP, ADP, and citrate, which allows it to play a significant role in cellular energy homeostasis. PFK exists in multiple isoforms, with the muscle and liver forms exhibiting different regulatory properties to meet the metabolic demands of various tissues. The enzyme operates as a homotetramer or heterotetramer, depending on the isoform, and its activity is modulated by allosteric interactions, making it a vital control point in glycolysis. PFK is found in many organisms, including bacteria, plants, and animals, highlighting its evolutionary importance. The CAS number 9001-80-3 identifies this enzyme in chemical databases, facilitating research and applications in biochemistry and molecular biology. Understanding PFK's characteristics and regulatory mechanisms is essential for insights into metabolic disorders and potential therapeutic targets.
Formula:Unspecified
Synonyms:
  • 6-Phosphofructo-1-kinase
  • 6-Phosphofructokinase
  • 6-Phosphofructokinase (E.C. 2.7.1.11)
  • 6-Phosphofructose-1-kinase
  • <span class="text-smallcaps">D</span>-Fructose-6-phosphate 1-phosphotransferase
  • ATP-dependent phosphofructokinase
  • ATP:<span class="text-smallcaps">D</span>-fructose 6-phosphate 1-phosphotransferase
  • ATP:D-fructose 6-phosphate 1-phosphotransferase
  • D-Fructose-6-phosphate 1-phosphotransferase
  • E.C. 2.7.1.11
  • See more synonyms
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Found 2 products.
  • CymitQuimica logo
    Targetmol
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    Phosphofructokinase

    CAS:
    <p>Phosphofructokinase, a crucial glycolytic enzyme, catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate in the glycolysis pathway. Its activity is inhibited by the binding of Phosphoenolpyruvate (PEP), which regulates the rate of glycolysis. Additionally, Phosphofructokinase is utilized in the measurement of fructose-6-phosphate (fructose-6-phosphate) levels.</p>
    Color and Shape:Solid

    Ref: TM-T200040

  • Fructose-6-phosphate Kinase
    Biosynth
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    Fructose-6-phosphate Kinase

    CAS:
    <p>Fructose-6-phosphate kinase (Phosphofructokinase, PFK, EC 2.7.1.11) is an enzyme that catalyzes the following reaction:  F6P + ATP ⇌ F1,6BP + ATP  One unit of PFK will convert 1.0 μmole of fructose 6-phosphate and ATP to fructose 1,6-diphosphate and ADP per minute at pH 9.0 at 30 °C.</p>
    Purity:Min. 95%

    Ref: 3D-FF171528

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