Phosphoglycerate kinase (PGK) is an enzyme that plays a crucial role in the glycolytic pathway, facilitating the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate while transferring a phosphate group to ADP to form ATP. It is a key regulatory enzyme in cellular metabolism, particularly in energy production. PGK is a dimeric protein, meaning it consists of two identical subunits, and it is found in various organisms, including bacteria, plants, and animals. The enzyme requires magnesium ions as a cofactor for its activity, which is essential for stabilizing the negative charges on the phosphate groups during the reaction. PGK is characterized by its specificity for its substrates and its dependence on the cellular conditions, such as pH and temperature, for optimal activity. The enzyme is also subject to regulation by various metabolites, reflecting its role in energy homeostasis. Its CAS number, 9001-83-6, identifies it in chemical databases, facilitating research and application in biochemistry and molecular biology.

Phosphoglycerate kinase

9001-83-6: Phosphoglycerate kinase (PGK) is an enzyme that plays a crucial role in the glycolytic pathway, facilitating the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate while transferring a phosphate group to ADP to form ATP. It is a key regulatory enzyme in cellular metabolism, particularly in energy production. PGK is a dimeric protein, meaning it consists of two identical subunits, and it is found in various organisms, including bacteria, plants, and animals. The enzyme requires magnesium ions as a cofactor for its activity, which is essential for stabilizing the negative charges on the phosphate groups during the reaction. PGK is characterized by its specificity for its substrates and its dependence on the cellular conditions, such as pH and temperature, for optimal activity. The enzyme is also subject to regulation by various metabolites, reflecting its role in energy homeostasis. Its CAS number, 9001-83-6, identifies it in chemical databases, facilitating research and application in biochemistry and molecular biology.

<p>PGK is an enzyme that catalyzes phosphate transfer between 1,3-BPG and ADP, vital in glycolysis and gluconeogenesis.</p>

CAS 9001-83-6

Phosphoglycerate kinase

Phosphoglycerate kinase

Ref: TM-T76122