CAS 900152-72-9

Fmoc-Asp(OtBu)-(Dmb)Gly-OH

Description:

Fmoc-Asp(OtBu)-(Dmb)Gly-OH is a protected amino acid derivative commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The "Asp" refers to aspartic acid, which is an α-amino acid with a carboxyl side chain, contributing to the molecule's overall polarity and potential for hydrogen bonding. The "(OtBu)" indicates the presence of a tert-butyl ester protecting group on the side chain carboxyl group of aspartic acid, which can be removed under specific conditions to yield the free acid. The "(Dmb)" denotes a dimethylbenzyl group, which can influence the steric and electronic properties of the molecule. The "Gly" indicates the presence of glycine, the simplest amino acid, contributing to the overall structure and flexibility of the peptide. This compound is typically utilized in solid-phase peptide synthesis, where the protection and deprotection of functional groups are crucial for the successful assembly of complex peptides.

Formula: C₃₄H₃₈N₂O₉

Synonyms:

• N-((9H-Fluoren-9-Ylmethoxy)Carbonyl)-L-Alpha-Aspartyl-N-((2,4-Dimethoxyphenyl)Methyl)Glycine 1-(1,1-Dimethylethyl) Ester

Fmoc-Asp(OtBu)-(Dmb)Gly-OH

CAS: 900152-72-9

Dmb backbone protection completely prevents base-catalyzed aspartimide formation of the Asp(OtBu)-Gly motif during Fmoc-SPPS. The Dmb moiety is readily introduced by coupling this Fmoc-dipeptide. Contrary to the Hmb derivative, cyclic lactones cannot be formed during activation.

Formula: C₃₄H₃₈N₂O₉

Purity: 98.8%

Color and Shape: Light Beige Crystalline Powder

Molecular weight: 618.68

Ref: 01-4062763

Fmoc-Asp(OtBu)-(Dmb)Gly-OH

CAS: 900152-72-9

Formula: C₃₄H₃₈N₂O₉

Purity: 95%

Color and Shape: Solid

Molecular weight: 618.6735

Ref: IN-DA00H1JF

(S)-2-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-N-(2,4-dimethoxybenzyl)-4-oxobutanamido)acetic acid

CAS: 900152-72-9

(S)-2-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-N-(2,4-dimethoxybenzyl)-4-oxobutanamido)acetic acid

Purity: 95%

Molecular weight: 618.68g/mol

Ref: 54-OR1073724

Fmoc-Asp(OtBu)-(Dmb)Gly-OH

CAS: 900152-72-9

Fmoc-Asp(OtBu)-(Dmb)Gly-OH is a peptide that has been synthesized by solid-phase synthesis. It has been designed to specifically bind to Lysine residues in proteins and can be used as a model protein with specificities for lysines. The sequence of the peptide is Fmoc-Asp(OtBu)-Dmb-Gly-OH. Fmoc-Asp(OtBu)-Dmb-Gly-OH is a novel chemical ligation strategy that uses an amide bond between the terminal amino group on the lysine and the alpha carboxyl group on the dipeptide, Dmb-(Dmb)Gly. This peptide is used for protein homeostasis, cellular functions, and modifications of proteins.

Formula: C₃₄H₃₈N₂O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 618.67 g/mol

Ref: 3D-FF111381