Blood-coagulation factor Xa, also known as factor Xa, is a crucial enzyme in the coagulation cascade, playing a pivotal role in the blood clotting process. It is a serine protease that catalyzes the conversion of prothrombin to thrombin, which subsequently leads to the formation of fibrin clots. Factor Xa is produced in the liver and is activated by both the intrinsic and extrinsic pathways of coagulation. Its activity is tightly regulated by various inhibitors, including antithrombin and tissue factor pathway inhibitor, to maintain hemostatic balance. Factor Xa is also a target for anticoagulant therapies, such as direct oral anticoagulants (DOACs), which inhibit its function to prevent thromboembolic events. The enzyme is typically studied in the context of cardiovascular diseases and is essential for understanding both normal hemostasis and pathological conditions like thrombosis. Its CAS number, 9002-05-5, identifies it in chemical databases, facilitating research and clinical applications related to coagulation disorders.

Blood-coagulation factor Xa

9002-05-5: Blood-coagulation factor Xa, also known as factor Xa, is a crucial enzyme in the coagulation cascade, playing a pivotal role in the blood clotting process. It is a serine protease that catalyzes the conversion of prothrombin to thrombin, which subsequently leads to the formation of fibrin clots. Factor Xa is produced in the liver and is activated by both the intrinsic and extrinsic pathways of coagulation. Its activity is tightly regulated by various inhibitors, including antithrombin and tissue factor pathway inhibitor, to maintain hemostatic balance. Factor Xa is also a target for anticoagulant therapies, such as direct oral anticoagulants (DOACs), which inhibit its function to prevent thromboembolic events. The enzyme is typically studied in the context of cardiovascular diseases and is essential for understanding both normal hemostasis and pathological conditions like thrombosis. Its CAS number, 9002-05-5, identifies it in chemical databases, facilitating research and clinical applications related to coagulation disorders.

<p>PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.</p>

CAS 9002-05-5

Blood-coagulation factor Xa

Porcine Factor Xa

Ref: TM-TRP-00247