Trypsinogen is an inactive precursor (zymogen) of the enzyme trypsin, which plays a crucial role in the digestive process by breaking down proteins in the small intestine. It is produced in the pancreas and is released into the duodenum, where it is activated to trypsin by the enzyme enterokinase. Trypsinogen is a glycoprotein, characterized by its relatively large molecular weight and specific amino acid sequence that includes a signal peptide for secretion. The activation of trypsinogen involves the cleavage of specific peptide bonds, which is essential for its enzymatic function. This zymogen is stable under physiological conditions but can be denatured by extreme pH or temperature changes. Trypsinogen's activity is tightly regulated to prevent premature activation, which could lead to pancreatic damage. Its CAS number, 9002-08-8, is used for identification in chemical databases. Overall, trypsinogen is a vital component of the digestive system, ensuring that proteins are efficiently processed into absorbable units.

Trypsinogen

9002-08-8: Trypsinogen is an inactive precursor (zymogen) of the enzyme trypsin, which plays a crucial role in the digestive process by breaking down proteins in the small intestine. It is produced in the pancreas and is released into the duodenum, where it is activated to trypsin by the enzyme enterokinase. Trypsinogen is a glycoprotein, characterized by its relatively large molecular weight and specific amino acid sequence that includes a signal peptide for secretion. The activation of trypsinogen involves the cleavage of specific peptide bonds, which is essential for its enzymatic function. This zymogen is stable under physiological conditions but can be denatured by extreme pH or temperature changes. Trypsinogen's activity is tightly regulated to prevent premature activation, which could lead to pancreatic damage. Its CAS number, 9002-08-8, is used for identification in chemical databases. Overall, trypsinogen is a vital component of the digestive system, ensuring that proteins are efficiently processed into absorbable units.

CAS 9002-08-8

Trypsinogen